Infection of Chlamydia trachomatis and apoptosis of spermatogenic cells / 中华男科学杂志

<p><b>OBJECTIVE</b>To evaluate the relationship between infection of Chlamydia Trachomatis(Ct) and apoptosis of spermatogenic cells.</p><p><b>METHODS</b>Apoptotic spermatogenic cells were examined by Wright-Giemsa staining and the terminal deoxynucleotidyl transferase-mediated deoxyuridine triphosphate(dUTP)-biotin nick-end labeling(TUNEL) technique.</p><p><b>RESULTS</b>Apoptosis rate of Ct infective group was significantly higher than that of normal group(P < 0.01).</p><p><b>CONCLUSIONS</b>Ct infection may cause the apoptosis of spermatogenic cells, which affords an objective evidence for illustrating the mechanism of Ct-infection-induced male infertility.</p>