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Pakistan Journal of Pharmaceutical Sciences. 2014; 27 (5): 1295-1302
in English | IMEMR | ID: emr-195088

ABSTRACT

Fishery waste and by-products are valuable sources of raw material for recovery of antioxidant and bioactive 3tides


Due to the increased demand for protein hydrolysates with antioxidative properties by various sectors of nsumable food, health care and pharmaceutical industries, the present study focused in the production of fish protein olysate [FPH] by enzymatic digestion from the backbone of Rastrelliger kanagurta [Indian mackerel] and evaluated | antioxidant potential


The observed results of the degree of hydrolysis suggest that the rapid phase of proteolytic savage was occurred in the first 60 minutes of incubation and during this period, the rate of hydrolysis was found to be with increasing ratio of enzyme to substrate concentration


The result of the antioxidant properties clearly tficates that thel, 1- diphenyl-2 picrylhydrazyl [DPPH] radical scavenging efficacy of FPH was similar to that of Jtic antioxidants like butylated hydroxyl toluene [BHT]


The FPH also exhibited significant reducing power ability I great potential to inhibit lipid peroxidation in equivalence with that of synthetic and natural antioxidants such as fand a-tocopherol respectively


The overall findings of the study reveal that, FPH produced by tryptic digestion has able amount of bioactive peptides with potent antioxidant properties


The synthesized FPH is a good candidate irfurther development into a commercial food additive

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