ABSTRACT
Studies on pre-clinical toxicity were undertaken to determine the haematological and biochemical changes after administration of alcoholic extract of leaf-stalk of P. betle in rats and mice. Acute and chronic toxicity experiments were performed on mice and rats according to WHO protocol. Different doses of plant extractive were administered for toxicity studies on short and long term basis. Haematological, biochemical profiles and enzymatic studies (transaminases and phosphatases) indicated that the drug (plant extractive) was devoid of toxicity.
Subject(s)
Magnoliopsida/chemistry , Animals , Drug Evaluation, Preclinical , Enzymes/metabolism , Female , Kidney/drug effects , Liver/drug effects , Male , Mice , Organ Size/drug effects , Plant Extracts/administration & dosage , Plants, Medicinal/chemistry , RatsABSTRACT
Description of a new species of sandfly Phlebotomus sundarai sp. nov. collected from Kala-azar endemic blocks-Gosaba and Baruipur, of district South 24-Parganas, West Bengal is given.
Subject(s)
Animals , Endemic Diseases , Female , India/epidemiology , Leishmaniasis, Visceral/epidemiology , Male , Phlebotomus/anatomy & histology , Species Specificity , Urban HealthSubject(s)
Animals , Cattle/parasitology , Feeding Behavior , Host-Parasite Interactions , Humans , India , Insect Vectors , PhlebotomusSubject(s)
Animals , Ecology , Female , Insect Vectors , Larva , Leishmaniasis, Visceral/transmission , Oviposition , Phlebotomus/parasitology , Soil/parasitologyABSTRACT
In a model experiment, seed extracts were applied to different bacterial test organisms. Different fractions of seed extracts in petroleum ether (60-80 degrees C) of Lagerstroemia speciosa (Linn. ex. Murray) Pers. when applied to both Gram positive and Gram negative test bacteria, some fractions showed high antagonistic activity.
Subject(s)
Anti-Bacterial Agents/chemistry , Bacteria/drug effects , Ethers , India , Plant Extracts/pharmacology , Plants, Medicinal/chemistry , Seeds/chemistryABSTRACT
Extracts from different parts of plants (1) including seeds are reported to act upon pathogenic microorganisms. A few active principles were isolated. The present preliminary report shows significant role of the seeds of Dolichos biflorus (Linn), locally known as Kulthi, against some test organisms using different fractions of defatted seed extracts with methanol.