value of uterine artery doppler in assessment of development of pre-eclampsia in women at risk

To evaluate the role of Doppler study done in the second trimester of pregnancy in the prediction of pre eclampsia. Prospective clinical trial. Department of Obstetrics and Gynecology, Kasr El-Aini Hospital. One hundred pregnant women with singleton gestation, in the second trimester, at risk of pre-eclampsia were subjected to Doppler ultrasound at 18-26 wks to measure S/D ratio, Resistance index RI, Pulsatility index of the uterine artery PI, in addition to the presence or absence of a diastolic notch. All women were followed up till delivery. There were significant differences between patients who developed PIH [eleven cases] and those who didn't develop as regards Doppler parameters at mid trimester including PI. RI, S/D ratio and the presence of diastolic notch. Doppler ultrasound at midtrimester identifies group of women at high risk for the subsequent development of pre-eclampsia for whom we can start preventive regimens

Cervicovaginal fibronectin as a predictive marker for success of induction of labor in prolonged pregnancy compared with the traditionally used bishop score

To compare cervical fibronectin as predictive marker for success of induction of labor compared with the traditionally was Bishop Score. Setting: Kasr EL-Aini Hospital. Design: A prospective controlled trial. Participants and 100 fullterm singleton pregnant women undergoing labor induction due to postdatism were examined to determine Bischop score and cervicovaginal fibronectin was assessed using fast reacting membrane immunoassay. There was a highly significant difference in the success of labor induction between women with positive and negative fibronectin test results. P<0.001. Fibronectin compared to Bishop Score has Sensitivity of 64.5%, Specificity of 44.8%, Positive predictive value of 78.9%, Negative predictive value of 54.2%, accuracy = 73%. Fetal fibronectin is a simple, easy and sensitive test for prediction of successful labor induction in women with prolonged pregnancy. If fetal fibronectin test in negative, induction of labor should be considered in women only with high Bishop Score.