1.
Braz. j. infect. dis
;
10(6): 406-407, Dec. 2006.
Article
in English
| LILACS
| ID: lil-446743
ABSTRACT
Pegylated Interferon-alpha, combined with ribavirin, gives high sustained virological response in patients with hepatitis C virus, an important public health problem and one of the most frequent chronic infectious diseases worldwide. Though it has therapeutic benefits, treatment with IFN-alpha may be complicated by various side effects, especially symptoms of major depression and acute mania. Psychosis is a rare side effect, and its management usually includes discontinuation of IFN-alpha. We report a case of psychotic disorder that occurred during therapy with pegylated Interferon-alpha given associated with ribavirin. After good response to psychiatric treatment, it became possible to finish the anti-viral therapy.
Subject(s)
Humans , Male , Middle Aged , Antiviral Agents/adverse effects , Interferon-alpha , Polyethylene Glycols/adverse effects , Psychoses, Substance-Induced/diagnosis , Ribavirin/adverse effects , Antipsychotic Agents/therapeutic use , Drug Therapy, Combination , Hepatitis C, Chronic , Psychoses, Substance-Induced/drug therapy , Risperidone/therapeutic use
2.
Braz. J. Psychiatry (São Paulo, 1999, Impr.)
;
26(2): 138-138, jun. 2004.
Article
in Portuguese
| LILACS
| ID: lil-385242