ABSTRACT
Congenital Hemidysplasia with Ichthyosiform nevus and Limb Defects [CHILD] syndrome is a very rare syndrome. It is inherited as X-linked dominant trait. The cutaneous lesions and extracutaneous defects are peculiar; as they involve one half of the body. We present here two Jordanian cases of CHILD syndrome, a new born girl and her mother. Up to our knowledge these cases are the first reported cases of CHILD syndrome in Jordan. The rarity of this syndrome prompted us to report these two cases
ABSTRACT
The aim of the study was to assess the frequency of cutaneous manifestations in patients with chronic kidney disease on hemodialysis. A retrospective study, including 75 patients with chronic kidney disease at Prince Hashem Hospital in Al-Zarqa-Jordan, were seen and properly evaluated for their current skin problems. Their files were reviewed. Patients' age, sex, associated medical illnesses, underlying causes of renal failure, the duration of renal failure and the duration of hemodialysis were included. Descriptive statistical analysis was used. There were 31 female [41.3%] and 44 male [58.7%] patients, the mean age of the study group was 53.9 years, 66 patients [88%] complained of skin problems. The most common problem was xerosis in 61 patients [82.3%], pallor in 60 patients [80%], pruritus in 45 patients [60%], pigmentary changes in 45 patients [60%], oral mucosal changes were seen in 48 patients [64%], hair changes in 34 patients [45%], nail changes in 29 patients [39%] and other cutaneous changes such as purpura in 14 patients [18.6%], acquired perforating folliculitis in six patients [8%] and nephrogenic fibrosing dermopathy in two patients [2.7%].Cutaneous manifestations are very common in patients with chronic kidney disease undergoing hemodialysis. Pruritus was the most troublesome symptom and xerosis was the commonest finding. More attention to cutaneous changes may help to relieve some of patient's co-morbid symptoms and improve their quality of life
ABSTRACT
Sweet's syndrome is an autoimmune inflammatory condition, characterized by erythematous plaques infiltrated by neutrophils limited to the dermis. If the infiltrate just present in or extend to the subcutaneous tissue, then it will be labeled as subcutaneous Sweet's syndrome. Due to the rarity of this condition, its association with other medical conditions is inconclusive. Herein, we present a male patient who underwent cochlear implant after having progressive bilateral sensory neural hearing loss. Two months after the implant, he developed cutaneous lesions consistent with subcutaneous Sweet's syndrome, which were well controlled with systemic steroids and cyclosporine. Four previous cases of Sweet's syndrome followed by progressive bilateral sensory neural hearing loss were reported in the literature. Twenty-one cases of subcutaneous Sweet's syndrome associated with different medical conditions were reported so far. The present case is the first, up to our knowledge, of progressive bilateral sensory neural hearing loss that was followed by subcutaneous Sweet's syndrome