ABSTRACT
Background: Prematurity is a major obstetric complication that affects infants' growth and development, and is also a big cause of infant mortality across the world. Prematurity is associated with certain risk factors, such as age extremes, mother's diet and health, multiple pregnancies, maternal infections, maternal smoking, inadequate follow-up, and insufficient management of maternal chronic diseases
Aim: In this study we aim to study knowledge and attitude of pregnant women toward the prematurity causes and complication
Methodology: We conducted a cross-sectional study, of 2470 women who presented in king Abdulaziz University, Jeddah, Saudi Arabia from April 2017 to December
Conclusion: We noted that although most mothers were aware of the positive impact on their health by regular follow-up visits to physician, many of them were not largely informed of the common associated risk factors. Better prenatal counselling can help create better awareness
ABSTRACT
Background: asthma is the most common chronic illness that affects children. It is described by chronic airway inflammation, remodeling of the airway wall, and airway hyper-responsiveness to non-specific spasms in response to stimuli causing a reversible airflow obstruction. Leukotrienes are one of the primary chemical mediators of inflammation in asthmatic airway, therefore leukotriene modifiers are an important class of drug for treating asthma
Methodology: we conducted this review using a comprehensive search of MEDLINE, PubMed, and EMBASE, January 1981, through February 2017. The following search terms were used: asthma pathophysiology, chemokines, leukotriene, and leukotriene modifiers, Montelukast in asthma management
Aim: our aim was to understand in depth the pathophysiology of pediatric asthma, and to study the effect of leukotriene modifiers in asthma management
Conclusion: for management of pediatric asthma, the leukotriene modifiers play a key role. New studies have shown that they could help in reducing dose and dependency on inhaled corticosteroid for maintenance, and decrease the need of systemic steroids in exacerbation. Leukotriene modifiers can have a positive impact on future asthma management and requires more studies to be done in this subject