ABSTRACT
Background: Ovarian superovulation and increased follicle-stimulating hormone concentration for infertility treatment may be the risk factors of developed granulosa-cell tumor. The aim of this report is to introduce a case of granulosa-cell
tumor which was discovered after ovarian stimulation
Case: A 31-yr-old woman with clinical presentation of massive abdominal distention was referred to the gynecology and oncology department of an academic hospital, Mashhad University of Medical Sciences in Aug 2017. She had the history of secondary infertility and was undergoing In Vitro Fertilization protocol and ovarian stimulation, but, the cycle was canceled. The patient suffered from gradual abdominal distention one month after the end of IVF procedure despite pregnancy failure. 2-3 months after management of the ovarian hyperstimulation syndrome, investigation revealed large ovarian mass and increased tumor marker inhibin. Exploratory laparotomy was performed and revealed stage III ovarian cancer. The final pathology report indicated juvenile granulosa cell tumor. So, optimal surgical staging and cytoreductive surgery without fertility preserving were perfumed. Chemotherapy was recommended due to the advanced stage of ovarian cancer. Unfortunately, she experienced metastatic diseases in pelvic and abdomen in less than six months; and currently is receiving the second and third line chemotherapy
Conclusion: Persistent ovarian enlargement or ascites during or after infertility treatment should be carefully considered and managed
ABSTRACT
Liver metastatic disorders usually occur in patients with stomach, pancreas, breast, colon, and lung and etc tumor. About 30 percent of patients die because of malignancies, have liver metastases. Liver imaging examination is a fundamental preclinical test to predict patient's prognosis and is required to monitor treatment. Despite recent advances in radiologic examination, liver metastases are still remaining as a challenge in human oncology. It seems that US is a reliable alternate for CT scan in metastases detection. CT scan should be considered in patients are highly suspension for liver metastases, who have normal or undetermined US findings. The aim of this study was a brief review of radiologic assessment in liver metastases