ABSTRACT
Objective To explore the value of combined application of prenatal ultrasound and MRI in diagnosis of fetal agenesis of corpus callosum (ACC).Methods The fetal brain ultrasound and MRI examination were performed in 1 1 7 fetuses with enlarged posterior horn of lateral ventricle and diaphanous diaphragm reduction or disappearance,and compared with postpartum diagnosis.Results Among the 48 cases of postpartum ACC confirmed by MRI,40 cases were diagnosed by prenatal ultrasound and 45 cases by prenatal MRI,and the sensitivity of the two methods was 83.33%,93.75% respectively(P<0.05).The sensitivity of combined diagnosis was 95.83%. Conclusion Fetal craniocerebral ultrasound combined with MRI can accurately diagnose fetal ACC,especially improve the detection rate of partial corpus callosum deletion,and provide a reliable basis for clinical diagnosis.