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Surg. cosmet. dermatol. (Impr.) ; 9(2): 166-168, abr.-jun. 2017. ilus.
Article in English, Portuguese | LILACS | ID: biblio-880313

ABSTRACT

A amiloidose é entidade caracterizada pela deposição de uma proteína modificada. Pode acometer a pele depositando-se na derme papilar. Em geral cursa com máculas acastanhadas predominantes na região interescapular e raramente com formas generalizadas. O presente relato refere-se a paciente do sexo feminino com queixa de manchas hipercrômicas de aumento progressivo para todo o corpo. A dermatoscopia se mostrou extremamente eficaz para a localização dos diversos focos de incontinência pigmentar, que junto com os queratinócitos apoptótico constituem a base fisiopatológica para a formação da proteína amiloide.


Amyloidosis is characterized by the deposition of a modified protein. It can affect the skin by accumulating in the papillary dermis. In general, it develops with brownish maculae predominant in the interscapular region, and rarely coursing with generalized forms. This report describes a 59 year-old female patient who had had a spot in the lower back for 43 years, which in the last 8 years had progressively spread for the entire body. Dermoscopy has proven extremely effective in locating the various foci of pigmentary incontinence, which together with apoptotic keratinocytes constitute the pathophysiological basis for the formation of the amyloid protein.

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