ABSTRACT
Objective To explore the predictive value of Kinetics of white blood cell (WBC) elimination following induction chemotherapy for eider with acute myeloid leukemia(AML). Methods 71 elder with AML were reviewed. Chi-square and the Kaplan-Meier methods were used to identify the relationship between the nadir WBC count and time to WBC nadir with efficacy and survival. Results 28 patients (39.44%) achieved a complete re-mission(CR),another 19 (26.76%) had a partial remission,17(23.94%) patients had a non-remission,and 7 pa-tients(9.86%)died. Overall survival over 3 years was about 11.27% (8 cases),over 2 years about 23.94 % (17 cases),and over 1 years about 47.89 % (34 cases). The low WBC nadir and high WBC nadir in the bone marrow CR (9.86% and 12.68%)and the total survival rate (8.45% and 11.27%)were lower than the median absolute WBC nadir (16.90%, 15.49%), but were no statistical discrepancy (χ23.32,1.22, P=0.77, 0.54). The pa-tients who achieved WBC nadir in less than or equal to 10 days in the bone marrow CR(12.68%) and the total sur-vival rate(8.45%) were statistical significantly higher than those achieved it in greater than 10 days(26.76%). The patients whose WBC attained at low level less than or equal to 3 days in the bone marrow CR(16.90%) and the total survival rate(12.68%) were statistical significantly higher than those greater than 3 days (22.54%) (χ2 15, 57,11.71,4.85,9.54,P=0.001,0.01,0.03,0.04). Conclusion WBC nadir in loss than or equal to 10 days and WBC attained at low level greater than 3 days may serve as a worse prognosis.
ABSTRACT
Objective To investigate the clinical effect of laser in situ keratomileusis(LASIK) for treatment of different degrees myopia.Methods According to the degree of myopia and astigmation,patients were divided into group A(-10.00D),and LASIK was performed in them with Schwind Esiris,a small,flying-spot excimer laser.Results At three months,it was found that 99.47% of the eyes in group A,82.93% in group B and 52.63% in group C had the uncorrected visual acuity of 1.0 or more;100% in group A,97.56% in group B and 89.47% in group C and 0.5 or more.Refractive degrees was stable between 1 to 3 months.No eyes lost more than 2 lines of BCVA.No severe complications occurred.Conclusion Using LASIK to treatment different degree myopia is secure,effective and divinable,especially in the group of mild-midder myopia.