[Paget's disease associated with vertebral hyperostosis about two cases]

The coexistence of Paget's bone disease [PBD] and diffuse idiopathic skeletal hyperostosis [DISU] of the spine is controversial and may have implications for the pathogenic mechanisms involved in these disorders. This association is illustrated by the following two cases. One of them presented a bilateral sciatica. The other case had a coxopathy and sciatica complicated by a cauda equina. The radiologtcal Investigations permitted the diagnosis as the two cases. The coexistence of Paget's disease and diffuse idiopathic skeletal hyperostosis is controversial and can have implications for the pathogenic mechanisms involved in these disorders. Diffuse idiopathic skeletal hyperostosis may facilitate extension of pagetic lesions