ABSTRACT
OBJECTIVE: Distinct aspects can influence the complication rates of computed tomography-guided percutaneous fine needle aspiration biopsy of lung lesions. The purpose of the current study is to determine the influence of radiological techniques and clinical characteristics in predicting complications from this procedure. SUBJECTS AND METHODS: A retrospective study was developed involving 340 patients who were submitted to a consecutive series of 362 computed tomography-guided fine needle aspiration biopsies of lung lesions between July 1996 and June 2004, using 22-gauge needles (CHIBA). Variables such as the radiological characteristics of the lesions, secondary pulmonary radiological findings, co-morbidities, and aspects concerning the procedure were studied. RESULTS: The diameters of the lung lesions varied from 9 to 140 mm, with a mean of 51.5 ± 24.3 mm and median of 40mm. The depth of the lesions varied from 10 mm to 130 mm, with a mean of 44 ± 20.9mm, and median median of 52 mm. Complications occurred in 52 (14.4 percent) cases, pneumothorax being the most frequent, with 40 (11.1 percent) cases, followed by hemoptisis with 7 (1.9 percent) cases, and hematoma with 4 (1.1 percent) cases. Lesions that did not contact the pleura, with normal pulmonary tissue interposition between lesion and pleura, had higher complication rates, with 22 (22 percent) cases, than lesions that contact the pleura, with 6 (9 percent) cases, with a statistically significant difference (p = 0.03). CONCLUSIONS: CT-guided percutaneous fine needle aspiration biopsy of lung lesions had a lower rate of complications in our study and presented more rates of complications on lesions that lack pleural contact.
Subject(s)
Female , Humans , Male , Middle Aged , Biopsy, Fine-Needle/adverse effects , Lung Diseases/pathology , Lung/pathology , Lung Diseases , Predictive Value of Tests , Retrospective Studies , Tomography, X-Ray Computed/methodsABSTRACT
A história natural da cirrose após um episódio de hemorragia das varizes foi definida a partir de ensaios clínicos em que indivíduos "controles" não receberam nenhum tratamento específico para evitar ressangramento. Os dados cumulativos indicam que mais de 70 por cento dos pacientes apresentarão recorrência hemorrágica dentro de primeiro ano do episódio inicial. O risco de ressangramento é maior imediatamente após a cessação do sangramento ativo e depois declina, chegando, após seis semanas, próximo aos valores basais. Cerca de 70 por cento de todos os pacientes não tratados morrem no primeiro ano após o primeiro episódio hemorrágico. As causas de morte incluem hemorragia variceal recorrente, insuficiência hepática, encefalopatia hepática, ascite progressiva e infecções. O tratamento ideal seria universalmente eficaz, seguro, disponível, fácil de administrar e barato. Por não existir este tipo ideal de tratamento, a escolha de determinada modalidade em relação à outra envolve considerações de sua relativa eficácia e segurança, disponibilidade e custos. As principais opções são escleroterapia endoscópica, ligadura endoscópica, terapia farmacológica com betabloqueadores e nitratos orais, inserção de TIPS (transjugular intrahepatic portosystemic shunt) e cirurgia