Hemorrhagic Fever with Renal Syndrome (HFRS) Virus Infected Hrman Umbilical Vein Endothelial (HUVE) Cells Decrease in Susceptibility to NK and LAK Cytotoxicity / 中国免疫学杂志

The cultured HUVE cells were infected with HFRS veruses. At different intervals after in-fection cytotoxicity of NK and LAK by 4 hours Cr release method. It was found that the infec-tion of endothelial cells inhibit the lytic activity of NK and LAK cells. Theinhibition. It is sug-gested that the deceased susceptibility of HFRS virus infected endothelial cells to NK and LAKcells may protect the viruses from the cellular immunity during the course of HFRS.