ABSTRACT
Liver cirrhosis is a condition which is defined histopathologically but cannot be diagnosed clinically without any non-invasive tests. There are various etiologies of cirrhosis such as alcoholic liver disease, chronic viral hepatitis B, C, and non-alcoholic fatty liver diseases. Liver, not only function as an organ for detoxification, conjugation, and synthesis but also it regulates body heat. Cirrhosis patients thus are prone to body heat loss and hyperthermia. We present a case with undiagnosed liver cirrhosis patient, 1st time presenting with altered sensorium, revealed as accidental secondary hypothermia with ECG changes of hypothermia. The patient treated for hypothermia only after which she recovered.
ABSTRACT
The Himachal Pradesh acute coronary syndrome registry highlighted a prehospital delay of 780 min. Additional door-to-needle time delay by 1 h increases the hazard ratio of death by 20%. We conducted a retrospective (group 1) and a prospective (group 2) analysis of 63 patients each to measure the impact of a fast-track protocol in the emergency department (ED) on the door-to-needle time in ST-elevation myocardial infarction (STEMI). The fast-track protocol involved zero cost to the hospital and saved 63 precious door-to-needle minutes for patients with STEMI. Thrombolysis in ED can save 33 precious minutes wasted in shifting patients to the coronary care unit.
ABSTRACT
Lymphocytic hypophysitis (LH) is a rare inflammatory disease of the pituitary gland. This condition strikingly shows female preponderance and commonly affects women during pregnancy or in the post-partum period. It’s a clinical presentation and radiological features may mimic pituitary adenoma. Though its treatment modality is uncertain steroid remains the 1st option for treatment. Here, we report an unusual case of LHin a 21-year-old female patient where initially, the patient presented with hyperadrenalism and secondary hyperthyroidism followed by pan-hypopituitarism (Addisonian crisis) which is attributed to initial autoimmune destruction of the gland followed by subsequent fibrosis. Thus, it is a rare case report which exquisitely explains this rare presentation and such cases should be investigated thoroughly since there are many differential and response to steroids is remarkable
ABSTRACT
Cardiovascular system diseases are playing the outstanding role in the cause of morbidity and mortality in dialysis patients. Left ventricular hypertrophy is one of the universal structural abnormalities in patients on regular dialysis
Objective: The target of the study was to search out the frequency of left ventricular hypertrophy in end stage renal disease patients on maintenance hemodialysis
Study design: Single center case-series study
Setting: Department of Nephro-Urology, Liaquat University of Medical and Health Sciences Jamshoro
Period: Begin from 1[st] March, 2013 to 30[th] August 2013
Results: Total numbers of patients were seventy three. Thirty three patients were male and 40 were female. Mean age of the patients was 44.19 years. High blood pressure was the most typical cause of nephropathy that is as certain in twenty 9[39.7%] cases pursue by Diabetes and Chronic Glomerulonephritis in twenty [27.4%] in each, renal stone in four [5.5%], unresolved acute renal failure four[5.5%] and Chronic Tubulointerstitial nephritis in two[2.7%] patients. Left ventricular hypertrophy was ascertained in nineteen [26%] patients
Conclusion: Our study concedes the high frequency of left ventricular hypertrophy in dialysis patients
Subject(s)
Humans , Male , Female , Adult , Middle Aged , Renal Dialysis , Kidney Failure, Chronic , EchocardiographyABSTRACT
Objective: To discover the burden of focal segmental glomerulosclerosis in patients of nephrotic range proteinuria [i.e.>3.5gm/24 hours/ 1.73m[2] body surface area]
Study design: A case series study
Place and duration: At the department of Nephrology Jinnah Post Graduate Medical Centre from 1st May 2011 to 30th Nov 2011
Methodology: Patients with nephrotic range proteinuria diagnosed by 24 hours urinary protein [>3.5gm/24 hours/1.73m[2] BSA] were included. Serum creatinine, total proteins, serum albumin, 24 hour urinary proteins, creatinine clearance, coagulation profile as well as renal biopsy was performed in every patient. In renal biopsy <50% glomerular involvement with involvement of a portion of the glomerular tuft was confirmed as patients having the focal segmental glomerulosclerosis
Results: The mean age of the patients was 25.93 +/- 5.923 years. Out of 144 patients there were 38[26.38%] females and 106[73.31%] males. There were 67[46.5%] patients with focal segmental glomerlusclerosis with nephrotic range proteinuria
Conclusion: The burden of focal segmental glomerulosclerosis in patients with nephrotic range proteinuria is high
ABSTRACT
Several strains of actinomycetes were isolated from soil samples collected from various localities ofAjmer district. These isolates were tested for their antagonistic proerties against few test organisms viz. Bacillus subtilis, Escherichia coli, Pseudomonas aeruginosa, Staphylococcus sp., Saccharomyces cerevisiae and Aspergillus niger. Some of these actinomycete strains exhibited antimicrobial activity against bacteria, no antifungal activity was observed. Six such isolates were selected for detailed morphological, cultural, physiological and biochemical studies for identification. Five of these were identified as members beloging to the genus Streptomyces and the remaining one belonging to the genus Actinoplanes.