ABSTRACT
Multisystem inflammatory syndrome (MIS) is a rare and severe post-infectious inflammatory disorder involving multiple systems (cardiovascular, gastrointestinal, dermatologic, nervous system, and haematological) without significant respiratory involvement. It is predominantly seen in children but sometimes in adults, usually after 3-6 weeks of COVID-19 infection or vaccination. It is postulated to be due to immune dysregulation. This case report adds to the limited literature available on post COVIDMISin adults, emphasizing how to reach the diagnosis after ruling out other differentials. Timely initiation of treatment gives gratifying results in most patients.
ABSTRACT
Dengue is a common mosquito-borne infection in India. We reported a rare Pharyngeal cervical brachial (PCB) variant of Landry Guillain Barre syndrome (LGBS) associated with the dengue virus infection. The pathogenesis seems to be molecular mimicry between gangliosides and microbial lipo-oligosaccharides. PCB usually presents with oropharyngeal or cervicobrachial weakness. Therefore, it must be recognised early and distinguished from conditions presenting with cephalocaudal progressing weakness, such as Myasthenia Gravis, Miller-Fisher syndrome, botulism, diphtheria, porphyria or brain stem stroke. The aim of the study was to add to the limited literature on the PCB variant of LGBS after dengue infection and shed some light on presentation and management options for this rare entity.