Role of single serum progesterone assay in threatened abortion as a predictor of viable pregnancy.

Background: Low progesterone levels have been linked to increased risk of miscarriage in first trimester of pregnancy. Methods: The observational, cross-sectional study was conducted over 100 pregnant females in first trimester of pregnancy < 12 weeks. All patients were subjected to sonography to confirm pregnancy & serum progesterone level testing immediately after admission and before initiation of treatment. Result: After analysis of the results, cut off value of serum progesterone as determined in this study came out to be 9.9 ng/ml with 94.9% sensitivity & 92.7% specificity. Conclusion: The value of serum progesterone estimation was of great help in differentiating between viable and non-viable pregnancy.

An Observational Study to Assess the Role of Uterine Artery Doppler in Prediction of Intrauterine Foetal Growth Restriction.

Background: The present study was planned to assess the role of uterine artery Doppler in the prediction of IUGR and Pre-eclampsia in the department of obstetrics and Gynaecology at NIMS Medical College during a span of one year (Nov 2013-Oct 2014). Methods: One hundred pregnant women with singleton pregnancy at 18-20 weeks period of gestation were subjected to uterine artery Doppler study and later repeated at 24-26 weeks of gestation. Results: It was observed that 38% patients had abnormal outcome with 20% patients with IUGR , 12% with PE, 6% with both IUGR and PE. Conclusion: By inclusion of uterine artery Doppler study in routine practice and timely intervention fetomaternal morbity and mortality can be greatly reduced.

Correlation Between D&C, USG and Hysteroscopy Findings in Diagnosing a Cause for Abnormal Uterine Bleeding.

Introduction: Abnormal uterine bleeding (AUB) is the most often encountered gynecological problem. A newly coined term describes the condition wherein there is any deviation from a normal menstrual pattern. An estimated 5% women aged 30-49 years consult a gynecologist each year for treatment. This makes it imperative to accurately diagnose and treat the cause. This study aims at judging the place of diagnostic hysteroscopy in obtaining an accurate diagnosis of the etiology of AUB and amp; outlining a mode of treatment. This is done by correlating the findings on hysteroscopy and those found on a dilation and curettage (D&C) and ultrasonography (USG). Material and methods: This prospective study was performed in the Dept. of Obstetrics and Gynecology, National Institute of Medical Sciences, Jaipur. Fifty cases of AUB were chosen based on inclusion and exclusion criteria. The patients were subjected to routine investigations, USG, D&C and hysteroscopy. The findings of the three were compared and analyzed. Results: AUB was most common between 30-39 years (44%). Maximum patients had complaints since 3-6 months (50%). Menorrhagia was the most common presenting complaint (46%). Normal findings were observed in 40% cases with D&C, 16% with USG, 22% with hysteroscopy. Abnormal findings were seen in 60% cases with D&C, 84% with USG, 78% with hysteroscopy. The over-diagnostic role of USG is also highlighted. Conclusion: This study reveals the superior ability of hysteroscopy in evaluating patients with AUB, when compared to D&C and USG. These findings are in agreement with those of many other studies.