ABSTRACT
Background & Objectives: To study the prevalence of HIV, HBsAg, HCV & syphilis in blood donors. Methods: The seroprevalence of HIV, HBsAg & syphilis among voluntary and replacement donors was analyzed for a period of 16 years (January 1996 to December 2011) and for HCV for a period of 10 years and 7 months (June 2001 to December 2011) at Department of Immunohaematology & Blood Transfusion, Civil Hospital, Ahmedabad. In this period, a total of 2, 81,665 donors were tested, out of which, 2, 00,903 (71.3%)were replacement donors and 80,762 (28.7%)were voluntary donors. HIV, HBsAg & HCV were tested by ELISA method and syphilis by RPR method. Results: Total seropositivity was 1071(0.380%) for HIV, 2900 (1.102%) for HBsAg, 599 (0.306 %) for HCV & 1522(0.540 %) for syphilis. In replacement donors, seropositivity for HIV was 891(0.443%), HBsAg was 2299(1.144%), HCV was 437(0.330%) & syphilis was 1130(0.562%). In voluntary donors, seropositivity for HIV was 180(0.222%), HBsAg was 601(0.744%), HCV was 162(0.257%) & syphilis was 392(0.485%). Conclusion: The present study indicates that higher seroprevalence rates for HIV, HBsAg, HCV & syphilis were observed in replacement donors as compared to voluntary donors.