ABSTRACT
Introduction: Ameloblastoma is benign locally aggressivedentine epithelial tumor. Mandible and maxilla are commonsites of involvement. Calretinin is specific marker and usefulto differentiate ameloblastoma from Keratocystic odontogenictumor. The rarity of site and presentation of lesion makes usreport this case.Case report: 46 year old female had recurrent nasalblockage. Polyps in right nostrils were seen on Rhinoscopy.Polypectomy was done for suspected antrochoanal polyps.Ameloblastoma was diagnosed on histopathology andconfirmed by Immunohistochemistry with Cytokeratin,Calretinin and WT1.Conclusion: Preoperative diagnosis by biopsy in unilateralnasal masses should be carried out to expect the unexpected.Immunohistohemistry should be performed in cases havingrare site to confirm the diagnosis.
ABSTRACT
A 58 year old male, chronic smoker, with diabetes mellitus (Type II), residing in Madhya Pradesh presented with dysphagia, hoarseness, odynophagia and significant weight loss. Microlaryngoscopy showed reddish ulcerated area involving valleculae, and pharyngo-epiglottic fold. Histopathological examination showed foamy macrophages containing Histoplasma capsulatum. Patient initially responded to Azoles, relapsed three months after stopping the treatment and presented with oral lesions. Biopsy showed H. capsulatum, histologically as well as on culture. The mycelial phase converted to yeast phase on B.H.I.A. at 37 degrees C confirming the isolate as H. capsulatum. The patient responded well to amphotericin B.