1.
Indian J Exp Biol
;
1999 Feb; 37(2): 143-6
Article
in English
| IMSEAR
| ID: sea-58708
ABSTRACT
Methanolic extract (ME) of the leaves of V. negundo potentiated significantly the sleeping time induced by pentobarbitone sodium, diazepam and chlorpromazine in mice. ME possesses analgesic properties and potentiated analgesia induced by morphine and pethidine. ME also showed significant protection against strychnine and leptazole induced convulsions. The results suggest that ME exhibits CNS depressant activity in a dose dependent manner.