ABSTRACT
Background: Estimation of time since death is one of the most important object of post-mortem examination. Many degenerative changes begin to take place in the body immediately or shortly after death. Kidney is one of the most important excretory organs of human body, its undergo series of gross as well as histological changes. Methods: This study was performed in department of anatomy in close association with the department of forensic medicine & toxicology and pathology, Pt. J. N. M. medical college and DBRAM hospital Raipur (C.G.) India, during study period November 2012 to October 2013. Study was done on 50 human cadavers (Study subjects). Kidney was obtained from dead bodies during post-mortem examination. In each case kidney was studied histologically. Data was compiled in MS excel and checked for its completeness and correctness and then it was analyzed. Results: In 48-60 hour increasing temperature, one case show very severe change was seen. Microscopic changes in kidney were increasing (mild to moderate, moderate to severe, severe to very severe) as temperature increases. Conclusion: In the present study earliest remarkable postmortem histological changes were seen in DCT. Finding of present study will be useful for forensic experts.
ABSTRACT
Background: Tobacco consumption in various forms in recent years is a proven risk factor and contributes substantially to the emerging epidemic. Increasing tobacco use and its impact on physical and psychosocial health is a worldwide public health concern affecting the early youth and whole life of the individuals. Tobacco is used in different forms and health effects are seen irrespective of the form in which it is used. Smokeless tobacco is found to be as addictive and harmful as smoking. Objectives: To assess the prevalence and factors influencing smokeless consumption among high school students in Raipur city. Methods: Study design: Cross-sectional, Study area: 16 selected high schools of Raipur city, in which 12 were government schools and 4 private schools. Study subjects: 1006 high-school students, Sampling technique: Two stage cluster sampling according to probability proportional to size, Study tool: Predesigned pretested questionnaire. Statistical analysis: Data was entered in Microsoft excel sheet and analyzed in Epi info 7 software. Results: The mean age of students in the study was 15 years. The prevalence of smokeless tobacco consumption was 10%. Majority male 80.9% were users, mean age of initiation was 13 years (SD 7.07), Peer pressure (76%) was the reason for initiation. Pocket money 57.1% found to be the major source of purchasing. Strong association of family member tobacco use and promotional advertisement were found. Conclusion: Study reflects smokeless tobacco use was prevalent among adolescent students and there is a need for targeted interventions to reduce the risk and deleterious consequences.
ABSTRACT
Background: Fine Needle Aspiration Cytology (FNAC) is a useful, safe and cost effective tool that is used in the diagnosis of lesions in various organs. Even though the literature on FNAC of soft tissue masses is relatively scarce, a large amount of interest has developed in this area in the last few years due to the low cost of the procedure, low incidence of complications, feasibility and high therapeutic efficiency. So the present study was undertaken to study the nature of various soft tissue tumors by FNAC and to compare the cytological diagnosis with the results obtained by biopsy. Methods: All cases 713 (Prospective-217 and Retrospective 496) included in present series were taken up for study. Aspiration of soft tissue lesions were performed following the technique of Zajicek et al. Smear was prepared, stained and examined. Histopathological details were available in 140 cases. Data was compiled in MS excel and checked for its completeness, correctness and then it was analyzed. Results: Total number of 11,560 FNAC was done in six and half year’s period from 1st April 2003 to 30th September 2009. Out of the total 713 cases of soft tissue tumors, 71.25% were reported as benign and 28.75% as malignant. Soft tissue tumors were more common in males in comparison to females, with M: F-1.63:1. Accuracy of FNAC for benign and malignant soft tissue tumours was 88.1% and 92.9% respectively. Conclusion: The overall diagnostic accuracy of FNAC in the present study was found 90%. FNAC is a safe and reliable method of recognizing benign and malignant soft tissue tumors and in most instances histological sub typing is possible. Cytological diagnosis must be based on strict cytological criteria and well controlled ancillary techniques.
ABSTRACT
Background: Infection with human immunodeficiency virus type-1 and its end stage, acquired immunodeficiency syndrome is the major public health challenge of modern time. A variety of exogenously acquired infectious agents appear to influence the pace of HIV replication, the destruction of CD4+ T cells, and HIV transmission to infants and sexual partners. More persistent elevations in plasma HIV levels have been seen in patients with chronic infections (such as those with tuberculosis and herpes and hepatitis viruses), and such co-infected patients have a more rapid loss of CD4+ T cells and an increased rate of progression to AIDS and death. Within India, variable co-infection rates have been reported from region to region. With the above background, the present study was undertaken to study the seroprevalence of hepatotropic viruses (Hepatitis B virus and Hepatitis C virus) in HIV-positive individuals attending the Integrated Counselling and Testing Centre (ICTC) in Mayo hospital of Nagpur city, Maharashtra, India. Methods: The current prospective study was conducted in the department of microbiology, Indira Gandhi government medical college and Mayo general hospital, Nagpur (Maharashtra) from August 2005 to August 2007. All the patients attending ICTC were included in the study. 300 HIV negative matched controls were also included in the study. All the individuals who were positive for HIV infection were selected for this study and further tested for the presence of hepatitis B surface antigen (HBsAg) and anti-HCV antibodies. Data was compiled in MS excel. Then it was analyzed using online statistical calculator and chi square test were applied with value of P <0.05 was considered statistically significant for interpretation of finding. Results: Maximum numbers of HIV positive patients (38.8%) were in age group of 31-40 years. Present study showed male preponderance in HIV positive patients. Males showed a slightly high seroprevalence of HBsAg (9.21%) compared to females (7.57%) among HIV positive patients. The difference in positivity of two viral agents studied in HIV positive patients was highly significant as compared to HIV-negative individuals (P <0.001). Conclusion: On the basis of the findings that the co-infection of hepatotropic viruses (HBV and HCV) were significantly higher in HIV positive cases than controls, the study concludes that the chronic viral hepatitis is a serious concern in HIV-infected patients. Thus, there is an urgent need to ensure the screening of the same in HIV-infected patients.
ABSTRACT
Lifestyle diseases characterized by those diseases whose occurrence is primarily based on the daily habits of people and are a result of an inappropriate relationship of people with their environment. The main factors contributing to lifestyle diseases include bad food habits, physical inactivity, wrong body posture, and disturbed biological clock. Lifestyle diseases are the most common causes of disability, morbidity and premature mortality. They account for 52% of deaths, 43% Disability Adjusted Life Years (DALYs) and 62% of total disease burden in India. Life style disease can be prevented through focused and comprehensive public health intervention by establishment of Healthy Life Style Centre (HLSC). HLSC will be a comprehensive approach which will provide health services for Non-Communicable diseases under the one roof. The HLSC will offer consultation, learning, counselling and testing facilities regarding Diabetes and other Non-Communicable diseases (NCD). Life style diseases can be prevented through public health intervention by special task force and policy document related to life style disorders.