ABSTRACT
A total of 405 cases of fever who were either admitted to the Hospital or attended in paediatric out patient Department or Emergency of Medical College Hospital, Calcutta between January '95 and November '95 were included in the study. Majority of cases presented with usual features of malaria like fever with chill and rigor, hepatosplenomegaly, pallor. Apart from these, complicated manifestations like shock, convulsion D.I.C and jaundice were also observed. Some unusual presentations with severe diarrhoea, dehydration and features like that of acute viral respiratory tract infection were highly confusing in terms of clinical diagnosis. P. falciparum was observed in 35.5% of cases. Overall therapeutic response to chloroquin was good, However, two patients died of cerebral Malaria. Five cases of severe malaria were caused by P. vivax however, other etiological features could not be found to attribute the severe nature of these illnesses.
Subject(s)
Animals , Antimalarials/therapeutic use , Child , Child, Preschool , Chloroquine/therapeutic use , Hospitalization/statistics & numerical data , Humans , India/epidemiology , Infant , Infant, Newborn , Malaria/classification , Malaria, Cerebral/mortality , Plasmodium falciparum/isolation & purification , Plasmodium vivax/isolation & purification , Quinine/therapeutic use , Severity of Illness Index , Urban HealthABSTRACT
An outbreak of Dengue Haemorrhagic Fever (DHF) occurred in Calcutta between September and December, 1990. Children and young adults were the major victims. Haemorrhagic manifestations and shocks were the main features in most of the hospitalised cases. Five mouse pathogenic agents were isolated from 105 acute cases and all were identified as DEN-3. HI and CF test with 55 paired sera revealed evidence of dengue infection in 33 (60 per cent) and flavivirus group reaction including dengue in 17 (30.9 per cent). It was for the first time, that DEN-3 was considered to be the etiologic agent for DHF in Calcutta.
Subject(s)
Adolescent , Adult , Biological Assay , Child , Child, Preschool , Complement Fixation Tests , Dengue/epidemiology , Dengue Virus/classification , Disease Outbreaks , Enzyme-Linked Immunosorbent Assay , Female , Hemagglutination Inhibition Tests , Humans , India/epidemiology , Infant , Male , Population Surveillance , Serotyping , Urban PopulationABSTRACT
A nosocomial outbreak of neonatal septicemia due to K. pneumoniae occurred in nursery during June-July, 1991. Klebsiella pneumoniae (Klebocin type 314) was recovered from blood of 33 (70.2%) of 47 neonates with septicemia. Multiple drug resistance was observed in all the cases. The same strain of K. pneumoniae was recovered from the neonates and environment of nursery and labour room as well. The outbreak was attributable to environmental dissemination.