ABSTRACT
Hypopharyngeal cancers have worst prognosis among the all head and neck cancers. The aim of this study is to study the etiopathological factors, clinical presentation, treatment outcome and prognostic factors in relation to different treatment modalities of hypopharyngeal cancer. Over the period of two years 30 hypopharyngeal malignancy cases were taken for the study and their etiology, clinical presentation, treatment modality and prognostic factors were studied and discussed. It was found that smoking and poor oral hygiene is the important causative factors. Among the patients only carcinoma of pyriform fossae were found. It was commonly seen in between 5th to 7th decade of life. Histopathologically they are squamous cell type and were moderately to poorly differentiate. Most of the patients presented at stage IV and stage III.Management was done with a combination of radiotherapy and chemotherapy. The treatment outcome was more or less the same regardless of the treatment modality chosen.