Blockade of CD28-B7 and CD40-CD40 ligand interactions induces long-term heart allograft survival and donor-specific tolerance in mice / 中华器官移植杂志

50 days),whereas third party skin grafts were vigorously rejected.Conclusion Blockade of CD28-B7 and CD40-CD40 ligand interactions resulted in long-term allograft survival and donor-specific tolerance in mouse cardiac transplantation without chronic rejection.