1.
Article
in English
| IMSEAR
| ID: sea-157532
ABSTRACT
Langerhans cell histiocytosis (LCH) is a complex disease characterized by proliferation of the Langerhans cells. The clinical course is variable and ranges from a solitary lytic bone lesion or skin lesion with complete remission to a multisystem disorder with possible lethal outcome. The diagnosis is suspected by clinical signs and symptoms and radiological features commonly in craniofacial bones and skin lesions. Diagnosis is confirmed by biopsy and immunohistochemical studies. We present case of a 8 year old child presenting with proptosis, diabetes insipidus and hypopigmented macules on chest and back showing bilateral distribution which is a rare presentation. Skin biopsy revealed the diagnosis of Langerhans cell histiocytosis.
Subject(s)
Child , Exophthalmos/diagnosis , Exophthalmos/epidemiology , Exophthalmos/etiology , Humans , Histiocytosis, Langerhans-Cell/complications , Histiocytosis, Langerhans-Cell/diagnosis , Male , Pigmentation Disorders/diagnosis , Pigmentation Disorders/epidemiology , Pigmentation Disorders/etiology
2.
Article
in English
| IMSEAR
| ID: sea-157435
Subject(s)
Adolescent , Adult , Blood Donors/analysis , Blood Donors/blood , Blood Donors/physiology , Enzyme-Linked Immunosorbent Assay/methods , Enzyme-Linked Immunosorbent Assay/statistics & numerical data , Female , Hepatitis B Surface Antigens/analysis , Hepatitis B Surface Antigens/blood , Hepatitis B Surface Antigens/isolation & purification , Humans , Latex Fixation Tests/methods , Latex Fixation Tests/statistics & numerical data
3.
Article
in English
| IMSEAR
| ID: sea-157355