Ocular manifestations in lipoid proteinosis: A rare clinical entity.

Lipoid proteinosis is a rare autosomal recessive genodermatosis with abnormal lipid protein complexes deposition in different parts of the body, especially in the skin and mucus membranes of the upper aerodigestive tract. Though ocular involvement in lipoid proteinosis is rare, ophthalmologists may encounter diverse ocular complications accompanying this syndrome in clinical practice. We describe a case of lipoid proteinosis involving bilateral eyelids with pathognomonic moniliform blepharosis in a 33‑year‑old gentleman who presented with the complaints of itching of eye lids on and off since 10 years.

Misoprostol Induced Rupture of Unscarred Uterus

Misoprostol is a prostaglandin E1 analogue and very efficient uterotonic drug. The US Food and Drug Administration (FDA) has listed a range of side effects such as hyperstimulation, uterine tetany, meconium-stained amniotic fluid, uterine rupture, maternal shock, maternal death, foetal bradycardia and foetal death. Rupture of uterus during labour with hypertonic contractions is a rare complication which is potentially life threatening to both mother and foetus. Due to increased risk of hyper stimulation, meconium-stained liquor and ruptured uterus with misoprostal uterine contractility and FHR must be monitored throughout induction the ideal dosage cannot also be specified.