Research progress of Luminal B breast cancer / 肿瘤研究与临床

Luminal B breast cancer is a main subtype of breast cancer.Disease free survival and overall survival rate of patients with Luminal B subtype are lower than those of patients with Luminal A subtype.Luminal B breast cancer is often treated with chemotherapy and endocrine therapy,and anti-Her-2 therapy is also essential for Luminal B/Her-2 positive breast cancer,but the prognosis is still poor.With the increasing understanding of Luminal B breast cancer,new targets are developed and used for improving treatment effect.This review will describe the clinical and pathological features,factors affecting prognostic,common treatments and new therapeutic targets for Luminal B breast cancer.