ABSTRACT
Introduction@#Health care workers of First Central Hospital of Mongolia have vaccinated with three different vaccines against SARS-CoV-2. We detected SARS-CoV-2 N and S-RBD antibodies after 30-90 days of second dose of vaccination. @*Method@#Quantitation of antibodies to the spike protein of SARS-CoV-2 was performed for the detection of adaptive immune response in 291 HCWs vaccinated with Covishield, Sinopharm and Pfizer Biontech. Detection and quantitation of SARS-CoV-2 N and S antibodies were performed by the electrochemiluminesce assay Cobas e411, Roche. @*Result@#SARS-CoV-2-S-RBD IgG titer were negative 0%, weak positive 0.4%, positive 17.5%, strong positive 82.1% of 246 HCWs vaccinated with Covishield and were negative 2.8%, weak positive 8.5%, positive 57.1%, strong positive 31.4% of 35 HCWs vaccinated with Sinopharm. </br> In all HCWs vaccinated with Pfizer Biontech SARS-CoV-2-S-RBD IgG titers were strong positive. @*Conclusion@#Humoral immunity was produced in HCWs after two doses of Covishield vaccine 100%, Sinopharm 97.0%, Pfizer Biontech 100% respectively. Antibody titer was higher among younger age workers.
ABSTRACT
@#Ancient Mongolia has accumulated experiences from generation to generation and created independent system of body structure, healing and healthy living by developing treatments for illnesses due to long term changes in natural phenomena, extreme climatic conditions, lifestyle habits, habits and war related diseases. The system has become a major part of the culture of Mongolia and has been enhanced by medical knowledge from other countries which include India, Tibet, and Chinese medicine, as well as study of European medicine that has not been sufficiently explored. There has been no research on history when this medical care disseminated in Mongolia and using source in research.</br> Therefore, this study was conducted to clarify when European medical knowledge arrived in Mongolia, its history and people who made contributions. </br> Historical facts of when European medicine was first "imported" in Mongolia, were recorded in policy of King Enkh-Amgalan of Manchu Qing Dynasty, the activities of religious missionaries from Europe to Manchuria and Mongolia and documents related to infectious diseases by Russian Consulate in Urguu. Based on these facts, European medical knowledge disseminated in Mongolia from 1703. This knowledge has been slowly spreading as a form of prevention from infectious diseases from the south through Beijing and Inner Mongolia as well as from the north through Buryatia to Ikh Khuree, and in some provinces.