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1.
Clinics ; 70(12): 797-803, Dec. 2015. tab, graf
Article in English | LILACS | ID: lil-769709

ABSTRACT

OBJECTIVE: To analyze the flow of retrobulbar vessels in retinoblastoma by color Doppler imaging. METHODS: A prospective study of monocular retinoblastoma treated by enucleation between 2010 and 2014. The examination comprised fundoscopy, magnetic resonance imaging, ultrasonography and color Doppler imaging. The peak blood velocities in the central retinal artery and central retinal vein of tumor-containing eyes (tuCRAv and tuCRVv, respectively) were assessed. The velocities were compared with those for normal eyes (nlCRAv and nlCRVv) and correlated with clinical and pathological findings. Tumor dimensions in the pathological sections were compared with those in magnetic resonance imaging and ultrasonography and were correlated with tuCRAv and tuCRVv. In tumor-containing eyes, the resistivity index in the central retinal artery and the pulse index in the central retinal vein were studied in relation to all variables. RESULTS: Eighteen patients were included. Comparisons between tuCRAv and nlCRAv and between tuCRVv and nlCRVv revealed higher velocities in tumor-containing eyes (p <0.001 for both), with a greater effect in the central retinal artery than in the central retinal vein (p =0.024). Magnetic resonance imaging and ultrasonography measurements were as reliable as pathology assessments (p =0.675 and p =0.375, respectively). A positive relationship was found between tuCRAv and the tumor volume (p =0.027). The pulse index in the central retinal vein was lower in male patients (p =0.017) and in eyes with optic nerve invasion (p =0.0088). CONCLUSIONS: TuCRAv and tuCRVv are higher in tumor-containing eyes than in normal eyes. Magnetic resonance imaging and ultrasonography measurements are reliable. The tumor volume is correlated with a higher tuCRAv and a reduced pulse in the central retinal vein is correlated with male sex and optic nerve invasion.


Subject(s)
Adolescent , Adult , Aged , Child , Female , Humans , Male , Middle Aged , Young Adult , Retinal Artery/physiopathology , Retinal Neoplasms/physiopathology , Retinal Vein/physiopathology , Retinoblastoma/physiopathology , Blood Flow Velocity , Eye Enucleation , Magnetic Resonance Imaging , Neoplasm Invasiveness/pathology , Neoplasm Invasiveness/physiopathology , Optic Nerve Neoplasms/blood supply , Optic Nerve Neoplasms/pathology , Optic Nerve Neoplasms/physiopathology , Prospective Studies , Risk Factors , Retinal Artery/pathology , Retinal Artery , Retinal Neoplasms/blood supply , Retinal Neoplasms/pathology , Retinal Vein/pathology , Retinal Vein , Retinoblastoma/blood supply , Retinoblastoma/pathology , Statistics, Nonparametric , Tumor Burden , Ultrasonography, Doppler, Color/methods
2.
Arq. bras. endocrinol. metab ; 51(4): 575-580, jun. 2007. ilus, tab
Article in Portuguese | LILACS | ID: lil-457094

ABSTRACT

OBJETIVO: Avaliar o efeito da "laserterapia" na acuidade visual em portadores de retinopatia diabética avançada e sem queixas visuais. MÉTODOS: Desenvolveu-se estudo observacional descritivo em portadores de retinopatia diabética avançada e sem queixas visuais, submetidos a panfotocoagulação retiniana com laser de argônio. Foi realizado exame oftalmológico completo. Entre o 3° e o 5° meses do tratamento, foi repetido o exame inicial. Para comparação da acuidade visual, entre período pré e pós-tratamento, foi utilizado o teste não-paramétrico de Wilcoxon. RESULTADOS: A amostra foi constituída por 44 pacientes, totalizando 67 olhos, sendo que 37 (55,2 por cento) apresentavam retinopatia diabética proliferativa e 30 (44,8 por cento) não proliferativa grave ou muito grave. A acuidade visual pré-tratamento variou de 0,5 a 1,0 (média de 0,83 ± 0,17). Não houve alteração estatisticamente significante na acuidade visual (p= 0,057) pré e pós-tratamento no período estudado. CONCLUSÃO: Houve estabilidade visual pós-tratamento com a panfotocoagulação, o que enfatiza a necessidade de intervenções em fases mais precoces da retinopatia diabética para preservar a função visual.


PURPOSE: To evaluate the effect of laser treatment in the visual acuity caused by advanced diabetic retinopathy without visual complaints. METHODS: A descriptive observational study was developed in advanced diabetic retinopathy patients not presenting visual complaints. The patients were submitted to argon laser panretinal photocoagulation after ophthalmological examination as well as retinography and retinal angiofluoresceinography. The same initial exams were repeated between third and fifth months after the treatment. The non-parametric Wilcoxon test was employed for statistical evaluation between the visual acuities before and after the treatment. RESULTS: The sample involved 67 eyes of 44 patients. Of these 67 eyes, 37 (55.2 percent) presented proliferative diabetic retinopathy and 30 (44.8 percent) showed severe and severe non proliferative diabetic retinopathy. The visual acuity before the treatment ranged from 0.5 to 1.0 (mean 0.81 ± 0.16). There was no significant statistical difference between the visual acuity (p= 0.057) before and after the treatment during the follow-up period of five months. CONCLUSION: The visual stability after panretinal argon laser photocoagulation indicated the need of this treatment in early phases of diabetic retinopathy in order to preserve the visual function.


Subject(s)
Aged , Female , Humans , Male , Middle Aged , Diabetic Retinopathy/surgery , Laser Coagulation/methods , Retina/surgery , Visual Acuity , Diabetes Complications/surgery , Diabetic Retinopathy/etiology , Follow-Up Studies , Laser Coagulation/standards , Severity of Illness Index , Statistics, Nonparametric , Treatment Outcome
3.
Rev. bras. oftalmol ; 57(6): 481-7, jun. 1998. ilus
Article in Portuguese | LILACS | ID: lil-216956

ABSTRACT

A telangiectasia justafoveolar idiopática (TJI) é uma vasculopatia retiniana da idade adulta, pode causar baixa acuidade visual e ser de difícil diagnóstico. Estudou-se os prontuários de 19 pacientes com TJI usando-se a classificaçäo de GASS & BLODI. Observou-se 8 pacientes no grupo 1 (42 p/c), 11 no grupo 2 (58 p/c) e nenhum no grupo 3. Todos os do grupo 1 apresentaram doença unilateral, com as telangiectasias facilmente visíveis, depósitos lipídicos e edema cistóide de mácula. A idade média foi de 55,8 anos, com cinco pacientes do sexo masculino (63 p/c) e três do feminino (37 p/c). Todos os do grupo 2 tinham doença bilateral com telangiectasias evidenciadas apenas à angiofluoresceinografia. A idade média foi de 54,5 anos, com dois


Subject(s)
Humans , Male , Female , Adult , Middle Aged , Fluorescein Angiography/statistics & numerical data , Ophthalmoscopes/statistics & numerical data , Retina/abnormalities , Telangiectasis/diagnosis
4.
Arq. bras. oftalmol ; 60(1): 24-33, fev. 1997. ilus, tab
Article in Portuguese | LILACS | ID: lil-193534

ABSTRACT

Foram estudados 31 olhos com retinopatia proliferativa falciforme nos estágios III (9 olhos) e IV (22 olhos) de Goldberg em 20 pacientes com genótipo SC. A idade média foi de 31,7a (variaçäo: 19-55; DP:9,74). O total de 98 lesöes proliferativas, ou Sea Fan (SF) foram analisadas quanto ao tamanho, número por olho e extensäo circunferencial. Foi feita a correlaçäo destas duas últimas variáveis com a presença de hemorragia vítrea (HV). Dos 22 olhos no estágio IV, apenas 7 (31,81 por cento) apresentavam diminuiçäo de acuidade visual relacionada à HV. Dividindo-se o comprometimento circunferencial em intervalos de 15§, concluiu-se que houve correlaçäo entre este e a presença de HV (P=0,0476). A extensäo circunferencial de até 30§ ocorreu em 9,09 por cento dos olhos no estágio IV e em 44,45 por cento no III (P=0,0195). Dos 98 SFs, 31,63 por cento tinham 30§ ou menos de extensäo circunferencial e mais da metade (51,01 por cento) 45§ ou menos. Näo houve correlaçäo entre o ndmero de SFs e a presença de HV. Concluiu-se que olhos com extensäo circunferencial de SF maior que 30§ têm maior probabilidade de apresentar HV (estágio IV) e que os SFs säo, em sua maioria, lesöes pequenas de 7 a 8mm de extensäo


Subject(s)
Humans , Male , Female , Middle Aged , Adult , Anemia, Sickle Cell/complications , Hemoglobinopathies/complications , Retinal Neovascularization , Vitreous Hemorrhage
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