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Arq. bras. oftalmol ; 83(1): 73-75, Jan.-Feb. 2020. graf
Article in English | LILACS | ID: biblio-1088954

ABSTRACT

ABSTRACT We describe three patients who had previous heart diseases and nonproliferative diabetic retinopathy with clinically significant diabetic macular edema. They underwent unilateral dexamethasone intravitreal implantation. Without ophthalmological treatment in the fellow eye, patients showed marked bilateral improvement in best-corrected visual acuity, optical coherence images, and macular thickness values. These findings provide evidence of the bilateral effect of dexamethasone intravitreal implantation, which may be clinically useful in patients for whom the systemic effects of the drug may affect their general health.


RESUMO Descrevemos três pacientes que tiveram doenças cardíacas prévias e retinopatia diabética não proliferativa com edema macular diabético clinicamente significativo. Eles foram submetidos a implante intravítreo de dexametasona unilateral. Sem tratamento oftalmológico no olho contralateral, os pacien tes apresentaram uma melhora bilateral significativa na melhor acuidade visual corrigida, nas imagens de coerência óptica e nos valores da espessura macular. Esses achados fornecem evidências sobre o efeito bilateral do implante intravítreo de dexametasona, que pode ser clinicamente útil em pacientes para os quais os efeitos sistêmicos da droga possam afetar a saúde geral do paciente.


Subject(s)
Humans , Male , Female , Middle Aged , Aged , Aged, 80 and over , Dexamethasone/administration & dosage , Macular Edema/drug therapy , Diabetic Retinopathy/drug therapy , Glucocorticoids/administration & dosage , Visual Acuity , Macular Edema/physiopathology , Tomography, Optical Coherence/methods , Diabetes Mellitus , Diabetic Retinopathy/physiopathology , Drug Implants , Intravitreal Injections
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