A case of pemphigus erythematosus / 대한피부과학회지

We present here, a case of pemphigus erythematosus developed in a 31-year-old woman, who had been suffering from repeated episode, of remission and exacerbation with several erythematous, and somewhat oozing patche accompanying a mild pruritus or her face, upper part of the back and anterior chest. In serological studies, she had antinuclear antiboc@lies at. a titer of 1:160. Histopathological finding showed subcorneal bullae. Immunofluorescent study revealed IgG and C, deposition in the intercellular space of the epidermis and along the de rmoepidermal junction.

Kaposi's Sarcoma Associated with Gastric Involvement

We report a case of classic Kaposi's sarcoma (KS) in a 67-year-old man, who had multiple cutaneous lesions of the feet and left hand as well as an internal involvement of the stomach. The histopathologic findings showed typical features of KS as a mid-dermal tumor composed of vascular proliferations, vascular slits, spindle cells, extravasated erythrocytes and deposits of hemosiderin. Analysis of T-cell subpopulations showed decreased T4 lymphocytes and in-creased T8 lymphocytes; the ratio of T4M lymphocytes was decreased. Natural killer cell activity was also decreased. These findings suggest a possible relationship between immunological abnormalities and the pathogenesis of this disease. The patient's serum was negative for antibodies to the human immunodeficiency virus (HM). This report describes a case of classic KS with immunological abnormalities and internal involvement and possible pathogenetic mechanisms are discussed.

A Case of Tinea Incognito / 대한피부과학회지

We report a case of tinea incognito occurring in a 47-year-old woman who deveoped erythematous papules and scaly patches on whole body after taking corticosteroid therapy intermittently over a period of 3 months. Direct smear and culture for fungus of the lesions demonstrated hyphae and C. albicans and T. mentagrophytes, which confirms the diagnosis. The lesions disappeared three months after systemic and topical antifungal therapy.

A Study of Allergen Prick Test Reactivity and Peripheral Blood Eosinophil and Total Serum IgE Levels in Patients with Atopic Dermatitis and Urticaria / 대한피부과학회지

Common environmental allergens play an important role in the pathogenesis of atopic dermstitis and urticaria via type I hypersensitivity reaction. The present study was undertaken to observe the prick test reactivity to common environmental allergens and peripheral blood eosinophil and total serum IgE levels in 20 patients of atopic dermatitis, 26 patients of chronic urticaria and 27 patients of artificial urticaria The results were as follows : 1, The psitive reactivities of allergens in patients with atopic dermatitis, chronie urticaria and artificial urticaria were 75.0%, 84.6% and 66.7%, respectively. 2. The positive reactivities of the inhalant allergens were more common than those of the food allergens, but statistically significant difference was found only in patients with chronic urticaria. 3. The most frequent allergen in prick test reactivity was D. farinae. 4. In patients with atopir, dermatitis, chrcnic urticaria and artificial urticaria, peripheral blood eosinophilias were encountered in 31.3%, 30.4%, and 25.0%, respectively. And statisticnlly significant elevations of eosinqphils in the prick test positive groups were observed in patients with atopic dermatitis. 5. ln patients with atopic dermatitis, chronic urticaria and artificial urticaria, elevati

A Case of Erythema Elevatum Diutinum Developed on the Unusual Sites / 대한피부과학회지

We report a case of 77-year old male with erythema elevatum diutinum, associated with pancytopenia, which developed on the unusual sites. Erythematous or brownish nodules developed on the face, neck, trunk, upper extremities and tongue. Histopathological examination of skin and tongue lesions showed perivascular infiltration of neutrophils, lymphocytes and nuclear dusts, and deposition of fibrinoid material within and around the vessel walls. His skin lesions improved slightly with systemic corticosteroid therapy.

A Case of Pityriasis Rubra Pilaris Treated with Etretinate / 대한피부과학회지

We report herein a case of pityriasis rubra pilaris in a 39-year-old male, who had erythematous scaly patches on the face, trunk and extremities for one year. The skin lesion showed well defined plaques on the elbow and knee joint areas, and exfoliative hyperkeratotic sheets with fissures on the palms and soles. He had no family and past history of such skin lesion. He was treated with etretinate lmg/kg/day for 1 week initially, and then tapered off 0.5mg/kg/day for 5 weeks with marked improvement. There was no exacerbation and recurrence of the skin lesion for about 1 year.