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0.05).Conclusions The chemotherapeutic embedding radioactive particle 125Ⅰ combined with GP is safe,feasible,and effective to the therapy of senile-inoperable NSCLC.
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To observe the clinical outcome of degenerative lumbar spondylolisthesis treated by TFC, transpedicle instrument and bone graft, transpedicle instrument and TFC, respectively, from May 1995 to Aug. 2000, 106 patients with degenerative lumbar spondylolisthesis were conservatively treated. According to Meyerding classification system of lumbar spondylolisthesis, 56 cases were classified as degree 1, 47 cases as degree 2, 3 cases as degree 3. The patients were followed up from 6 months to 10 years and 2 months, averaged 38 months. According to different operative methods, the patients were divided into 3 groups: TFC group, transpedicle instrument and bone graft group, transpedicle instrument and TFC group. Among the 31 cases in TFC group, 22 cases were followed up, the excellent rate was 95 5%. Among the 42 cases in transpedicle instrument and bone graft group, 35 cases were followed up, the anatomical reduction rate was 83%, the excellent rate was 94 8%. Among the 33 cases in transpedicle instrument and TFC group, 28 cases were followed up, the anatomical reduction rate was 81%, the excellent rate was 96 4%. According different indications, TFC and pedicle screw systems were all effective for spondylolisthesis. They had a lower complication rate. The use of spinal instrumentation is a valuable adjunct to achieve lumbosacral fusion in patients having undergone decompressive surgery for the spine.
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Objective To explore the feasibility of implantation of a composite of tendon, grains of cancellous bone and bone morphogenic protein (BMP) wrapped in antologous periosteum to substitute lunate bone lunatum in the treatment of Kienbock disease. Methods 42 Japanese big ear rabbits were randomly divided into two groups. In group A periostum wrapping a composite of tendon, grains of cancellous bone and bone morphogenic protein (BMP) was implanted. In group B only tendon wrapped by periostum was used. Both of them were respectively implanted into rabbits' suprapatellar bursa, the physiological environment of which seemed to be similar to that of the carpal joint after extirpating the lunate bone in human being. The composites were removed in 1,2,4,8,12,16 and 24 weeks after the operation. X ray imaging, gross, histological and EM changes at varies intervals were observed. And CT value of the composite was statistically analyzed (Stata 4 0). Results Periosteum wrapped BMP/grains of cancellous bone could induce bone and cartilage formation. In group A, newly formed bone could be found at 2 weeks. Rounded bony body with cortex and bone marrow was found to be formed by the implanted composite at 8 weeks. No degenerative changes were observed up to 24 weeks. In group B, the composite didn't form bony body in 24 weeks. In different periods, statistically significant difference in CT value between group A and B was found ( P