ABSTRACT
Background: Solanum xanthocarpum grows in parts of India as a wild herb. The active principles of this plant are Solasodine, Carpesterol, ?-Sitosterol, and Diosgenin. Pharmacological effects such as hypoglycemic, hepatoprotective and hypotensive activity of S. xanthocarpum have been reported. Solasodine, an active component of this plant is reported to have antioxidant activity. Aims and Objectives: The objective of this study is to evaluate the anticancer and anti-obesity property of S. xanthocarpum. Materials and Methods: This study was carried out in Department of Pharmacology, Government Kilpauk Medical College, with laboratory support from Life Teck Research Center, Chennai. Both dry and fresh leaves of S. xanthocarpum were taken and evaluated for anticancer property using MCF cell line and anti-obesity activity using Pancreatic Lipase inhibition activity. Results: There was significant decrease in cell viability with increase in concentration of both dry and fresh leaves which shows anticancer activity. With increase in concentrations of leaf extracts, the inhibition of pancreatic lipase was found but in comparison to Orlistat the standard treatment, the effect was very less. Conclusion: Based on above results, it is concluded that S. xanthocarpum has good anticancer and minimal anti-obesity activity. Further investigations are required to identify the actual phytoactive component.
ABSTRACT
Background: E-learning or electronic learning is a popular modality to address the educational needs of a population. In the context of medical education, E-learning is useful but has its limitations. Aim and Objectives: This study was conducted among 2-year MBBS students of a Government Medical College in South India to know their knowledge, attitude, and practice of E-learning and also to learn from their experiences during the COVID pandemic. Materials and Methods: After obtaining informed consent, students were asked to fill up a questionnaire containing 15 questions in Google Forms and submit it. Results: This study shows that more than 70% of students consider themselves capable of using computers for everyday activities. They also reported using search engines and online animations for updated medical information. However, they preferred their course content to be delivered through blended learning, a combination of classroom and E-learning. The students reported poor internet connectivity as a major limitation in E-learning. They also suggested having a separate website for each college where the teaching material can be uploaded by the faculty and can be accessed by all the students of the institution. Conclusion: From this study, it can be concluded that a majority of students have good knowledge and are already using E-learning modalities. They are also open to the idea of blended learning for clinical cases.