ABSTRACT
Un cas de faux kyste traumatique du pancreas est etudie. Il s'agit d'une affection rare. Celui-ci est le premier cas connu au Gabon a ce jour. Les auteurs sont surpris par les dimensions monstrueuses prise par la tumefaction et surtout par la duree entre le traumatisme initial et le debut de la symptomatologie. Ils regrettent de ne pas disposer de moyens d'investigation appropries. L'indication operatoire etait formelle. Malgre l'avenement de la chirurgie endoscopique; le traitement chirurgical classique occupe toujours une place de choix dans cette pathologie. Les deux interventions les plus utilisees sont les derivations internes et les resections. Les auteurs justifient la derivation interne par l'anciennete de la masse et par le mauvais etat general du patient
Subject(s)
Pancreatic Pseudocyst/pathologyABSTRACT
Three enzymes have been described in malaria merozoites: a serine-protease and two phospholipases. The parasite serine-protease is necessary for parasite entry into the red blood cell. This enzyme is synthesized by intraerythrocytic schizonts as a glycolipid-anchored membrane precursor, harbouring a performed serine-protease active site but not detectable proteolytic activity. Detection of the enzymatic activity correlates with the solubilisation of the enzyme by a parasite glycolipid-specific phospholipase C in merozoites. A third enzyme has been detected with glycolipid-degrading activity, presumably a lipase A. These activities participate in a biochemical cascade originating with the attachment of the merozoite to the red blood cell, including the translocation of the phospholipase C to the membrane-bound protease, the solubilisation/activation of the protease and its secretion at the erytrocyte/parasite junction and ending with the entry of the parasite into the host cell. Both the phospholipase C and the lipase A might generate secondary messages in the merozoite. Our current knowledge concerning these enzymes is presented