Experimental transvitreal retinopexy with cyanoacrylate tissue adhesive

We have developed an experimental model of rhegmatogenous retinal detachment during vitreous surgery with intraoperative repair by fluid-gas exchange. Special instrumentation was developed to allow the transvitreal application of n-buty 1-2-cyanoacrylate mixed with iophendylate to the retinal break. The chorioretinal adhesions produced with this tissue adhesive were compared in the same model to those produced by transscleral retinal cryopexy. The chorioretinal adhesions produced by the cyanoacrylate tissue adhesive were immediate in onset, stronger than cryopexy and longlasting in effect