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1.
Arq. bras. cardiol ; 65(2): 129-138, Ago. 1995. ilus, tab
Article in Portuguese | LILACS | ID: lil-319377

ABSTRACT

PURPOSE--To assess in a consecutive series of patients, the diagnostic accuracy of dipyridamole echocardiography and to compare its prognostic power with that from other tests. METHODS--Seventy eight patients prospectively were underwent to dipyridamole echocardiography (DET) and coronary arteriography for diagnostic and post-infarction investigation. The majority was underwent to treadmill stress test and Tc99MIBI-dipyridamole planar myocardial scintigraphy. Eleven variables with possible prognostic importance were analyzed in a stepwise model to identify independent predictors of events. RESULTS--Sensitivity and specificity for the presence of coronary artery disease (in non-M patients) and multivessel disease (in post-MI patients) were, respectively, 44, 91, 53 and 88. Mean follow-up was 21 +/- 9 months, during which there were four deaths, four unstable angina episodes, four nonfatal myocardial infarctions and eight revascularization procedures. By multivariate analysis, the only independent predictor of events was the change in wall motion score index from rest to peak stress. CONCLUSION--DET is a valuable alternative to exercise stress test and myocardial perfusion scintigraphy. Semiquantitative estimation of ischemic area during pharmacological stress is an important prognostic marker.


Subject(s)
Humans , Male , Female , Middle Aged , Echocardiography , Coronary Disease , Dipyridamole , Vasodilator Agents , Predictive Value of Tests , Prospective Studies , Sensitivity and Specificity , Technetium Tc 99m Sestamibi , Multivariate Analysis , Radionuclide Angiography , Coronary Angiography , Chi-Square Distribution , Prognosis , Exercise Test
2.
Arq. bras. cardiol ; 44(5): 339-345, maio 1985. ilus, tab
Article in Portuguese | LILACS | ID: lil-1572

ABSTRACT

Em 59 fonocardiogramas de 50 pacientes tendo fibrilaçäo atrial (FA) como única alteraçäo cardíaca, ou associada a outras doenças, mediu-se o tempo de espaço ventricular (TEV) e os intervalos R-R do eletrocardiograma. Para cada paciente foi confeccionado um gráfico correlacionando o TEV com o intervalo R-R anterior e calculados os coeficientes de correlaçäo e regressäo. O coeficiente de correlaçäo entre o TVE e o R-R precedente foi alto em todos os pacientes com FA, sendo mais elevado entre os portadores de estenose mitral (EM) (média 0,74 = 0,139) do que entre os sem esta doença (média 0,54 = 0,226). O alto coeficiente de correlaçäo obtido vem confirmar que as variaçöes da duraçäo do ciclo cardíaco interferem com o TEV e, em última análise, com o volume sistólico. Em relaçäo ao coeficiente de regressäo, foram obtidos resultados bem mais elevados nos portadores de EM, principalmente quando näo operados e nos sem EM mas insuficiência ventricular esquerda (IVE), o que distinguia estes dois grupos dos outros pacientes. Concluiu-se que o coeficiente de regressäo, em pacientes com EM, parece indicar grau de gravidade da obstruçäo mitral, sendo maior em pacientes com EM mais severa. Nos pacientes com IVE, é possível que o alto coeficiente de regressäo seja resultado da pressäo de enchimento ventricular esquerda aumentada


Subject(s)
Humans , Male , Female , Adult , Middle Aged , Atrial Fibrillation/physiopathology , Stroke Volume , Phonocardiography , Systole , Heart Ventricles/physiopathology
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