ABSTRACT
Objective@#COVID-19 pandemic affected the mental health of healthcare workers (HCWs) as well as their physical health. In this study, we aimed to evaluate the anxiety, depression and burnout levels of Turkish HCWs after the first period of the pandemic. @*Methods@#The participants filled sociodemographic data form, Hospital Anxiety and Depression Scale (HADS) and Maslach Burnout Inventory (MBI). @*Results@#In this study, 221 HCWs (68.8% female) with a median age of 28 (20−66) years were included. Concerning HADS cut-off points, 39.8% of the participants scored above the depression cut-off point, while 26.2% scored above the cut-off point for anxiety. The anxiety (HADS-A) and depression (HADS-D) scores of nurses and medical secretaries were significantly higher than the physicians. Also, the anxiety and depression rates of nurses were higher than both physicians and medical secretaries. Emotional exhaustion (MBI-EE) and depersonalization (MBI-D) scores were highest in nurses, followed by medical secretaries and physicians, respectively. In multivariate analysis, being a nurse (OR: 4.671, p = 0.044) or medical secretary (OR: 4.013, p = 0.048), requirement of using a mental health support line (OR: 4.641, p = 0.005), having any kind of addiction (OR: 2.562, p = 0.019) and being under antidepressant therapy (OR: 3.096, p = 0.036) significantly increased the risk of anxiety. However, in multivariate analyses, the only requirement of using a mental health support line significantly increased the risk of depression (OR: 8.542, p = 0.001). @*Conclusion@#Female HCWs, nurses and medical secretaries experienced higher levels of mental health symptoms than male HCWs and physicians.
ABSTRACT
Objectives: The aim of this study was to investigate the relationships between clinical features of rheumatic diseases and hematologic indices, including mean platelet volume [MPV], MPV/platelet ratio [MPR], platelet/lymphocyte ratio, and neutrophil/lymphocyte ratio [NLR]
Subjects and Methods: Rheumatoid arthritis [RA; n = 91], systemic lupus erythematosus [SLE; n = 51], systemic sclerosis [SSc; n = 39], and Behcet's disease [BD; n = 53] patients, and 55 healthy controls [HC] were enrolled. Hematological indices were calculated and one-way analysis of variance, Mann-Whitney U and chi 2 tests, and receiver operating characteristic [ROC] analyses were performed
Results: The MPV and MPR were higher in the SLE group than the RA group [p < 0.05 and p < 0.01, respectively]. ROC analysis indicated that MPV [area under the curve, AUC, 0.68, 95% CI 0.58-0.77] and MPR [AUC 0.69, 95% CI 0.59-0.78] were sensitive and specific markers for SLE against RA. The NLR was higher in the RA, SLE, and SSc groups compared to the HC group [p < 0.05, p < 0.001, and p < 0.01, respectively]. The NLR was higher in the active BD patients than those that were inactive [p = 0.008]. Besides, NLR was higher in patients with neuro-BD and patients with active genital ulcers compared to patients without neurological involvement [p < 0.01] and active genital ulcers [p < 0.05]
Conclusion: The MPV and MPR were significantly higher in the SLE group than in the RA group. They were also higher in the active than in the inactive BD patients. The MPV and MPR are useful diagnostic tools for SLE, and NLR reflects disease activity in BD. However, further research should be performed to standardize these tools