ABSTRACT
Linfomas näo Hodgkin de alto grau sao comumente relatados em pacientes com a síndrome da imunodeficiência adquirida (AIDS). Comprometendo com grande frequência o sistema nervoso central, particularmente as leptomeninges e os hemisférios cerebrais. O acometimento epidural é pouco frequente, variando de 3,5 por cento a 8,3 por cento de acordo com os registros da literatura. Os autores relatam o caso de um paciente de 27 anos de idade com AIDS, cuja manifestaçao clínica inicial da doença linfomatosa disseminada foi a mielite transversa associada à mielopatia vacuolar. Destaca-se a importância do diagnóstico diferencial precoce das mielopatias na AIDS, em virtude da alta malignidade da neoplasia e da evoluçao extremamente rápida nesses pacientes.
Subject(s)
Humans , Male , Adult , Spinal Cord Diseases/etiology , Lymphoma, Non-Hodgkin/etiology , Lymphoma, AIDS-Related/pathology , Myelitis, Transverse/etiology , Acquired Immunodeficiency Syndrome/complications , Vacuoles/pathology , Diagnosis, Differential , Spinal Cord Diseases/diagnosis , Spinal Cord Diseases/pathology , Lymphoma, Non-Hodgkin/complications , Lymphoma, Non-Hodgkin/pathology , Myelitis, Transverse/diagnosis , Myelitis, Transverse/pathology , Acquired Immunodeficiency Syndrome/pathologyABSTRACT
We report the case of a 52-year-old male heterosexual patient with acquired immunodeficiency syndrome (AIDS) and reactivation of Chagas' disease manifested by meningoencephalitis and myocarditis, diagnosed post-mortem. Unexplained reactivation of Chagas' disease should be included among the diagnostic criteria of AIDS in human immunodeficiency virus positive patients. On the other hand, AIDS should be considered in the differential diagnosis of patients with unexplained reactivation of Chagas' disease.