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2.
Rev. méd. Chile ; 134(4): 481-484, abr. 2006. ilus
Article in Spanish | LILACS | ID: lil-428549

ABSTRACT

Gastrointestinal stromal tumors (GIST) are lesions whose diagnosis and treatment have varied in the last decade. We report a 76 year-old male with a history of eight episodes of upper gastrointestinal bleeding. A duodenography showed an elevated lesion in the third portion of the duodenum with a central ulceration. It was initially managed with tumorectomy and primary closure of the duodenum. The pathological study of the surgical specimen revealed a low grade gastrointestinal stromal tumor. Three years later, the tumor recurred and pancreatoduodenectomy was performed. Due to the high risk of malignant potential, tumor size, number of mitoses and the presence of necrosis, imatinib mesylate was started. The patient had a satisfactory evolution, without evidences of recurrence after 15 months of follow up.


Subject(s)
Aged , Humans , Male , Duodenal Neoplasms , Gastrointestinal Stromal Tumors , Antineoplastic Agents/therapeutic use , Duodenal Neoplasms/drug therapy , Duodenal Neoplasms/pathology , Duodenal Neoplasms/surgery , Duodenal Ulcer/drug therapy , Duodenal Ulcer , Duodenal Ulcer/surgery , Gastrointestinal Hemorrhage/drug therapy , Gastrointestinal Hemorrhage , Gastrointestinal Hemorrhage/surgery , Gastrointestinal Stromal Tumors/drug therapy , Gastrointestinal Stromal Tumors/pathology , Gastrointestinal Stromal Tumors/surgery , Pancreaticoduodenectomy , Piperazines/therapeutic use , Proto-Oncogene Proteins c-kit , Pyrimidines/therapeutic use , Recurrence
3.
Rev. chil. cir ; 42(1): 62-4, mar. 1990. tab
Article in Spanish | LILACS | ID: lil-84535

ABSTRACT

Se analizó retrospectivamente 50 pacientes operados por contusión abdominal complicada entre enero de 1983 y septiembre de 1987. La mortalidad de los pacientes mayores de 45 años fue de 35,7% en relación a 19,4% para los menores de esta edad. Los pacientes intervenidos entre las 3 y 6 horas de ingreso fueron los de menor mortalidad (13%). Los órganos abdominales más frecuentes lesionados fueron: bazo con 36%, e hígado con 24%. En 58% hubo lesión extraabdominal asociada, en ellos la mortalidad fue de 37,9% y de 4,75% en los sin asociación. La mortalidad global alcanzó 24%


Subject(s)
Middle Aged , Humans , Abdominal Injuries/surgery , Fractures, Closed , Liver/injuries , Spleen/injuries , Abdominal Injuries/mortality , Retrospective Studies
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