ABSTRACT
In this study, we showed that neurons could be generated from adult canine bone marrow stem cells by culturing with DMSO/BHA/FeCl2. These neurons differentiated from the bone marrow stem cells formed neurites, expressed neuron-specific markers. This differentiation was enhanced by FeCl2. These results suggest that iron can effectively initiate differentiation of adult bone marrow stem cells into neurons.
Subject(s)
Adult , Humans , Bone Marrow , Cell Culture Techniques , Iron , Neurites , Neurons , Stem Cells , Tissue EngineeringABSTRACT
Hepatocellular carcinoma is one of the most common causes of death in Koreans. Most cases of hepatocellular carcinoma are beyond the stage of curative resection at the time of diagnosis due to extrahepatic metastasis as well as wide distribution of tumor in the liver. The lung is the most common site of extrahepatic metastasis but metastasis to gingiva is very rare in hepatocellular carcinoma. We report a case hepatecellular carcinoma with gingival methststasis in a 59 year old male patient.