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Rev. chil. dermatol ; 26(3): 272-278, 2010. ilus
Article in Spanish | LILACS | ID: lil-569983

ABSTRACT

Las queratodermias palmo plantares son un grupo diverso de trastornos caracterizados por el engrosamiento anormal de la piel de las palmas y pantas, que puede ser hereditario o adquirido. Este últimos se define como una hiperqueratosis no hereditaria, no friccionar, de las palmas y/o las plantas que afecta al 50% o más de estas superficies ocrales. Es un trastorno de múltiples etiologías, entre las cuales destacan: el climaterio, asociada a malignidad, a otras dermatosis, acuagénica, causada por infecciones, asociada a medicamentos, a enfermedades sistémicas, y la hiperqueratosis palmo plantar filiforme (queratodemia espinosa). El tratamiento tiende a ser sintomático y puede variar desde medidas simples a queratoliticos tópicos, retinoides sistémicos o cirugía reconstructiva. En algunas queratodermias especificas, como la climatérica y aquellas asociadas a hipotiroidismo, el tratamiento indicado es el reemplazo hormonal, y en las asociadas a malignidad, la extirpación del tumor habitualmente produce la mejoría de to hiperqueratosis.


Palmoplantar keratodermas are a diverse group of disorders characterized by an abnormal thickening of the skin of the palms and soles, which can be hereditary or acquired. The last form above mentioned is defined as a non-hereditary, non-frictional hyperkeratosis of the palms and/or soles that involves 50 percent or more of the surface of these acral areas. This is a disorder produced by multiple causes, among which highlight climacteric, associated with malignancies, related with another dermatoses, aquagenic, infectious, drug-related, related with systemic disease and palmar/plantar filiform hyperkeratosis (spiny keratoderma). Treatment tends to be symptomatic and may vary from simple advices to topical keratolytics, systemic retinoids or reconstructive surgery. In some specific keratodermas like the climacteric one and in those associated with hypothyroidism the recommended treatment corresponds to hormonal replacement and in those associated with malignancies the removal of the tumor usually results in improvement of the hyperkeratosis.


Subject(s)
Humans , Keratoderma, Palmoplantar/etiology , Keratoderma, Palmoplantar/therapy , Keratolytic Agents/therapeutic use , Adrenal Cortex Hormones/therapeutic use , Dermabrasion , Communicable Diseases/complications , Skin Diseases/complications , Neoplasms/complications , PUVA Therapy , Pharmaceutical Preparations/adverse effects , Retinoids/therapeutic use
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