1.
Egyptian Journal of Pharmaceutical Sciences. 1989; 30 (1-4): 23-8
in English
| IMEMR
| ID: emr-12807
ABSTRACT
This study sheds light on the pH-meter studies of the complexes of sulfamethoxypyridazine with trivalent transition metal ion, in order to obtain a comparison of the relative stability of complexions containing trivalent cations. An attempt was made to obtain the formation constants of the complexes of Cr[III] and Fe[III] with sulfamethoxypyridazine, a sulfonamide possessing pyridazine ring, which have not been widely studied and also to complete studies on the chelating tendencies of sulfa drugs. The study was made in different ionic strength of NaCl at 30 degrees and at one and the same ionic strength 0.1 M at 38 degrees. Thermodynamic parameters [delta G, delta H and delta S] were calculated at 30 degrees and 0.1 M [NaCl] ionic strength