ABSTRACT
Objective@#To explore the effect of introducing multi-dimensional care strategy based on the concept of cognitive goal implementation in patients with femoral head necrosis replacement.@*Methods@#From April 2016 to July 2018, 94 patients with femoral head necrosis were treated in Hainan Third People's Hospital. According to the digital table, the clinical subjects were named as study group and control group, 47 cases each. Among them, the control group carried out traditional intervention, while the research group carried out multi-dimensional care strategy based on the concept of cognitive goal implementation. The self-management ability, quality of life and satisfaction of the two groups were compared before and 4 weeks after the intervention.@*Results@#After intervention, the scores of life behavior, rest and sleep, exercise, diet, medication compliance, self-monitoring, psychological counseling and regular reexamination in the study group were (2.0 ± 0.6), (1.9 ± 0.5), (1.8 ± 0.3), (2.0 ± 0.5), (2.4± 0.7), (2.0 ± 0.5), (2.1 ± 0.7) and (2.1 ± 0.6) respectively, which were higher than those in the control group (1.6 ± 0.4). There were significant differences in scores (t = 10.268-20.369, P<0.05). The scores of physiological function, physiological function, social function, mental health, emotional function, vitality, somatic pain and general health in the study group after intervention were (80.6 ± 6.5), (43.7 ± 4.2), (75.1 ± 6.1), (69.5 ± 5.1), (50.9 ±4.4), (66.5 ± 5.0), (79.3 ± 5.2) and (65.9 ± 6.0) respectively, which were higher than those in the control group (67.3 ± 4.2).) There were significant differences in scores (t = 11.803-18.277, P<0.05). The good rate of target implementation in the study group was 89.4% (42/47), which was higher than that in the control group (65.9% (31/47). The difference was statistically significant (χ2 = 16.782, P<0.05). The nursing satisfaction of the study group was 97.9% (45/47), higher than that of the control group 85.1% (40/47). The difference was statistically significant (χ2=4.919, P<0.05).@*Conclusion@#Multidimensional care strategy based on the concept of cognitive goal execution can improve self-care ability and quality of life of patients with femoral head necrosis replacement, and improve patient satisfaction.
ABSTRACT
Objective To explore the effect of introducing multi-dimensional care strategy based on the concept of cognitive goal implementation in patients with femoral head necrosis replacement. Methods From April 2016 to July 2018, 94 patients with femoral head necrosis were treated in Hainan Third People's Hospital. According to the digital table, the clinical subjects were named as study group and control group, 47 cases each. Among them, the control group carried out traditional intervention, while the research group carried out multi-dimensional care strategy based on the concept of cognitive goal implementation. The self-management ability, quality of life and satisfaction of the two groups were compared before and 4 weeks after the intervention. Results After intervention, the scores of life behavior, rest and sleep, exercise, diet, medication compliance, self-monitoring, psychological counseling and regular reexamination in the study group were (2.0 ± 0.6), (1.9 ± 0.5), (1.8 ± 0.3), (2.0 ± 0.5), (2.4± 0.7), (2.0 ± 0.5), (2.1 ± 0.7) and (2.1 ± 0.6) respectively, which were higher than those in the control group (1.6 ± 0.4). There were significant differences in scores (t = 10.268-20.369, P<0.05). The scores of physiological function, physiological function, social function, mental health, emotional function, vitality, somatic pain and general health in the study group after intervention were (80.6 ± 6.5), (43.7 ± 4.2), (75.1 ± 6.1), (69.5 ± 5.1), (50.9 ±4.4), (66.5 ± 5.0), (79.3 ± 5.2) and (65.9 ± 6.0) respectively, which were higher than those in the control group (67.3 ± 4.2). ) There were significant differences in scores (t = 11.803-18.277, P<0.05). The good rate of target implementation in the study group was 89.4% (42/47), which was higher than that in the control group (65.9% (31/47). The difference was statistically significant (χ2=16.782, P<0.05). The nursing satisfaction of the study group was 97.9% (45/47), higher than that of the control group 85.1% (40/47). The difference was statistically significant (χ2=4.919, P<0.05).Conclusion Multidimensional care strategy based on the concept of cognitive goal execution can improve self-care ability and quality of life of patients with femoral head necrosis replacement, and improve patient satisfaction.
ABSTRACT
Objective To discuss the correlation between MTHFR gene polymorphism and unexplained recurrent spontaneous abortion.Methods A case control study was used in this study,140 patients with unexplained recurrent spontaneous abortion(UR-SA) (abortion group)and 143 cases of normal women(control group)were recruited.Genomic DNA was obtained and extracted from the oral mucosa cells.Fluorescence quantitative PCR was used to examine the MTHFR gene polymorphisms,and Taqman-MGB technology was conducted to analysis the relationship between single nucleotide polymorphism and disease.Results There was statistically significant difference in the frequencies of C677T genotype and alleles between the two groups(P＜0.05).However,no significant difference in the frequencies of A1298C genotype and alleles between the two groups(P＞0.05).Conclusion MTHFR gene C677T polymorphism might be one of the genetic risk factors of URSA.
ABSTRACT
Objective To explore the association of lipid metabolism and bomocysteine with hypertensive disorders in pregnancy and observe the inflammatory reaction and the pathological change of placenta.Methods We conducted a prospective randomized placebo-controlled study.Seventy-four cases with hypertensive disorders in pregnancy were recruited as the experimental group and 77 cases of normal pregnant women were recruited as matched control group from Aug.2008 to Mar.2010.The relationship between lipid metabolism and homocysteine was analyzed.Results There was significant difference between the two groups in body-mass index before pregnancy(29.03±4.52 vs.23.99±5.90,t =5.88),cholesterol[(6.16±1.48)mmol/L vs.(5.01±1.05) mmmol/L,t =5.52],low density lipoprotein[(3.46±1.35) mmol/L vs.(2.26±0.86) mmol/L,t =6.54]and C-reactive protein[(29.04±14.90) mmol/L vs.(15.48±4.57) mmol/L,t =7.62](P ＜ 0.05).No significant difference was found on triglycerides[(3.29±1.03) mmol/L vs.(3.49±1.37) mmol/L],high density lipoprotein[(1.84±0.40) mmol/L vs.(1.88±0.35) mmol/L],homocysteine [(8.77±2.65) mmol/L vs.(8.40±2.03) mmol/L]and neonatal weight[(3547±519)g vs.(3431±461)g](P ＞ 0.05).Significant difference exists in placenta pathology of infarction(54.55％ vs.31.04％),villi dysplasia,fit nodules form and hypoxia(65.46％ vs.39.66％)(P ＜0.05).Conclusion We should detect lipid,homocysteine and C-reactive protein by dynamic combinational ways,pay more attention to women with high BMI before pregnancy,and value placenta pathology research on hypertensive disorders in pregnant women.This has high clinical significance in revealing the etiology of hypertensive disorders in pregnant women and improving pregnant outcomes.