Chemical Constituents， Pharmacological Effect， and Product Development of Eucommia ulmoides with Both Medicinal and Edible Values： A Review / 中国实验方剂学杂志

Eucommia ulmoides， a plant belonging to Eucommiaceae， has a history of medical use for over two thousand years in China. The dried bark and leaves of this plant are usually used as medicinal materials. Due to the high safety in clinical application， E. ulmoides leaves were officially recognized for both medicinal and edible use by the food safety evaluation in 2019， providing a valuable resource for the development of food and health products. According to the traditional Chinese medicine theory， E. ulmoides has the effects of nourishing the liver and kidneys， strengthening sinews and bones， and calming fetus. Modern research has shown that different parts such as the bark， leaves， flowers， and seeds of E. ulmoides contain similar chemical components， including phenylpropanoids， terpenoids， flavonoids， phenolic acids， steroids， and polysaccharides. E. ulmoides exhibits diverse pharmacological activities such as lowering blood pressure and blood lipid and glucose levels， preventing osteoporosis and possesses anti-tumor， anti-bacterial， antiviral， anti-inflammatory， antioxidant， and hepatoprotective effects. Therefore， it holds great potential for the development of products with both medicinal and edible values. This review systematically summarizes the chemical constituents， pharmacological activities， and representative medicinal and edible products of different parts of E. ulmoides. It is expected to provide theoretical references for the clinical application of E. ulmoides and its active components and the development and utilization of the products with both medicinal and edible values. This review contributes to a deeper understanding of the medicinal properties of E. ulmoides and provides guidance for further exploration of its applications in the healthcare field. As a plant with both medicinal and edible values， E. ulmoides is expected to attract more attention in future research and contribute to human health.

Genus Tetrastigma: A review of its folk uses, phytochemistry and pharmacology / 中草药·英文版

The genus Tetrastigma belongs to the Vitaceae family and contains over 100 species. This paper reviewed folk uses, chemical constituents, pharmacological activities, and clinical applications of the medicinal plants in the genus Tetrastigma. In addition, the paper also discussed the current problems for the further studies. Up to now, more than 240 compounds were reported from the genus Tetrastigma, covering 74 flavonoids, 14 terpenoids, 19 steroids, 21 phenylpropanoids, 14 alkaloids and others constituents. Among them, flavonoids are the major and the characteristic chemical constituents in this genus. Modern pharmacological studies and clinical practice showed that the extracts and chemical constituents of Tetrastigma species possessed wide pharmacological activities including antitumor, antioxidative, hepatoprotective, antiviral, anti-inflammatory, and analgesic activities. The information summarized in this paper provides valuable clues for new drug discovery and an incentive to expand the research of genus Tetrastigma.

Advances in radiation of internal mammary lymph nodes after breast-conserving or modified radical surgery for breast cancer / 国际肿瘤学杂志

With the development of the times, the comprehensive treatment technology of breast conserving or modified radical mastectomy plus radiotherapy for breast cancer has become more mature and perfect. As the first station of lymphatic drainage of breast, internal mammary lymph nodes have been paid much attention. At present, there is a controversy about whether the internal mammary lymph nodes are irradiated or not. Previous studies have shown that local lymph nodes irradiation containing internal mammary lymph nodes has survival benefit value. However, as a part of regional lymph nodse irradiation, internal mammary lymph nodes irradiation has also been proved to increase the toxicity of heart and lung, which leads to some research institutions and scholars to remain skeptical about internal mammary lymph nodes irradiation. In recent years, with the improvement of radiotherapy technology and equipment and the accumulation of clinical experience, more and more scholars tend to accept internal mammary lymph nodes radiotherapy. But we should pay attention to the indications of internal mammary lymph nodes irradiation, in order to select appropriate treatment options to achieve real benefits.