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Chinese Journal of Schistosomiasis Control ; (6)1989.
Article in Chinese | WPRIM | ID: wpr-677033

ABSTRACT

The antischistosomal effects of Levo-praziquantel (L-PZQ) compared with racemic prazi-quantel (dL-PZQ) in vitro on miracidium and cercaria of Schistosoma japonicum were reported in this paper. The results indicated that the schistosomicidal effect on the two larval stages of the parasite induced by L-PZQ (0. 2 ?g/ml) and double amount of dL-PZQ (0. 4?g/ml) had no significant difference. Miracidial stage was more sensitive to the drugs than the cer-carial stage. The schistosomicidal mechanism caused by L-PZQ was discussed briefly.

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