ABSTRACT
Introdução: O quelóide é uma alteração cicatricial de alta prevalência e difícil tratamento. Essa pesquisa é baseada em uma modalidade conjunta de efeito comprovado na literatura, a aplicação de corticosteróide intralesional associada à cirurgia. Algumas referências citam a importância da excisão intralesional do quelóide, baseando-se na experiência clínica dos cirurgiões. O objetivo desta pesquisa é avaliar se no tratamento do quelóide com corticosteróide intralesional mais excisão cirúrgica a manutenção ou não de tecido queloidiano nas bordas da ferida operatória influencia no índice de recidiva. Método: Estudo prospectivo que avaliou 42 pacientes em um total de 60 lesões queloidianas, no período de agosto de 2005 a janeiro de 2008, comparando três grupos cada qual com 20 lesões alocadas de forma aleatória. Foi realizada excisão intralesional no grupo 1; justalesional (sem margem macroscópica) no grupo 2 e extralesional (com margem de 2 mm) no grupo 3. O tratamento com corticosteróide intralesional foi realizado da mesma forma em todos os pacientes. A variável de desfecho foi clínica: índice de recidiva. Resultados: Após o acompanhamento de dois anos, a taxa de recidiva do quelóide foi de 20% no grupo 1, 45% no grupo 2 e 77,5% no grupo 3 (p=0,024). Conclusão: Quanto ao tratamento cirúrgico, justifica-se a excisão intralesional, mantendo as bordas do tecido queloidiano, por estar associada a menor índice de recidiva quando comparado à excisão justa ou extralesional.
Introduction: Keloid is a scar tissue abnormality of high prevalence and difficult treatment. This research is based on a scientific literature proved combined tactical, the intralesional corticosteroid injection associated with surgery. Some references cite the importance of intralesional excision of keloid, based upon clinical experience of a few surgeons. The objective is to assess the influence of maintaining or not keloid tissue in the surgical wound edges in the intralesional corticosteroid injection plus surgical excision method, in the recurrency of keloid. Methods: Prospective study with 42 patients in a total of 60 keloid lesions, from August 2005 to January 2008, comparing three groups, each one with 20 lesions randomly distributed. Intralesional excision was performed in group 1; with no macroscopic borders in group 2; and extralesional (2 mm borders) in group 3. The intralesional corticosteroid injection was performed the same way in all patients. The analyzed outcome was clinical: keloid recrudescency taxes. Results: After the two year follow-up, the keloid recrudescency taxes was about 20% in group 1, 45% in group 2 and 77.5% in group 3 (p=0.024). Conclusions: The intralesional excision is justified, for being associated with lower recrudescency taxes, when compared with excisions with none or 2 mm borders.
Subject(s)
Humans , Male , Female , Adolescent , Adult , Middle Aged , Cicatrix, Hypertrophic/surgery , Cicatrix/surgery , Adrenal Cortex Hormones/therapeutic use , Keloid/surgery , Wounds and Injuries , Methods , Recurrence , Diagnostic Techniques and ProceduresABSTRACT
PURPOSE: To perform a endoscopic gastrostomy by the introducer method with routine instruments used in a general hospital, without special instruments of special kits.METHODS: This procedure was performed in pigs (Sus scrofa domesticus) under observation for seven days and then submitted to euthanasia. The technique was evaluated for macroscopic and histologic parameters. RESULTS: All animals had a good evolution without major complications. Some minor complications ocurred like a rupture of Foley catheter balloon and subcutaneous space abscess.CONCLUSION: The percutaneous gastrostomy with routine general hospital instruments is sucessful performed, is safe, cheap and must be performed by skilled endoscopists.
Subject(s)
Animals , Male , Endoscopy, Gastrointestinal/methods , Stomach/surgery , Gastrostomy/instrumentation , Gastrostomy/methods , SwineABSTRACT
Introduction: Since 1991, we have done the tracheoesophageal shunt as described by Amatsu in candidates to a total laryngectomy. Our goal is to provide the patients a better speech rehabilitation that that obtained by the non-surgical techniques, and by doing so, lessen the oncological treatment impact on the patient's quality of life. Aim: This work revises the experience of our institution with the procedure during a 10 years period. Study design: Clinical retrospective. Material and method: We had 54 patients submitted to the procedure, 3 women e 51 men, with ages from 30 to 78 years old and a mean age of 59 years. All had scamous cell carcinoma, 10 from the piriform sinus, 2 from retrocricoide area, 6 from the supraglottis, 1 from the subglottis, 16 from the glottis and 19 were transglottic. According to the AJC staging system, 3 were stage II, 17 were stage III, 24 were stage IV and 10 were not staged. Previous radiotherapy as initial treatment had been done in 18 patients. During the laryngectomy, 33 patients had some type of neck dissection and in 15 of these patients the neck dissection was done bilaterally. A myocutaneous pectoralis major flap was needed in 5 cases and a deltopectoralis flap was used in one case. Postoperative radiotherapy was used in 20 patients. Local infections occurred in 36 percent of the cases, and all had a good outcome. One patient died in the early postoperative period. Results: Speech rehabilitation by the technique was successful in 70 percent of the cases. Aspiration occurred in 10 patients and, in 2 of these, the shunt had to be surgically closed. Conclusion: In conclusion, due to its low cost, good results with few complications, the Amatsu tracheoesophageal shunt continues in our service as the main technique for speech rehabilitation after laryngectomy