ABSTRACT
Samples of 1815 cerebrospinal fluid (CSF) were studied in a meningitis outbreak during 1989 in S ao Paulo, Brazil. Neisseria meningitis 56 per cent with 44 per cent type B, Haemophilus influenzae 17 per cent , from which 72 per cent in children (days to 3-year-old) and Streptococcus pneumoniae 14 per cent from which 60 per cent in children (day to 1-year-old) of 443 (24 per cent ) of all strains. Cytochemistry study showed: purulent or turbidity aspects in 70 to 79 per cent positive bacterioscopy or culture of CSF; white cells count > 500/mm3; glucose < 45 mg/dl; protein > 90 mg/dl in 90 per cent of all patients. We concluded that: CSF prognostic factors: (aspect and cytochemistry) were correlated with bacterial meningitis. Bacterioscopy and positive cultures were correlated to NM, SP and HI isolation from these patients (Goodman Test)
Subject(s)
Humans , Male , Female , Infant, Newborn , Infant , Child, Preschool , Child , Adolescent , Adult , Meningitis, Meningococcal/cerebrospinal fluid , Meningitis, Pneumococcal/cerebrospinal fluid , Meningitis, Haemophilus/cerebrospinal fluid , Cerebrospinal Fluid/metabolism , Cerebrospinal Fluid/microbiology , Haemophilus influenzae/isolation & purification , Histocytochemistry , Meningitis, Meningococcal/microbiology , Meningitis, Pneumococcal/microbiology , Meningitis, Haemophilus/microbiology , Neisseria meningitidis/isolation & purification , Streptococcus pneumoniae/isolation & purificationABSTRACT
Trata-se de paciente do sexo feminino, com 59 anos de idade, procedente de Itaporanga (SP), diabética e nefropata crônica, internada em virtude de surtos de pielonefrite e insuficiência renal aguda. Dentre outras medidas terapêuticas, recebeu transfusäo de sangue. Cerca de dois dias após a última transfusäo (sangue oriundo de doador, posteriormente identificado como chagásico) encontraram-se formas tripomastigotas de Trypanosoma cruzi em lâmina preparada para execuçäo de hemograma. Iniciou-se tratamento com Benzonidazol. A paciente cursou para pleuropneumonia e de secreçäo purulenta cirúrgica isolou-se Klebsiella spp. A septicemia conduziu a paciente ao êxito letal. Nenhuma lesäo tecidual foi observada no miocárdio, no sistema nervoso central, adrenal ou nos demais órgäos examinados