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Rev. nefrol. diál. traspl ; Rev. nefrol. diál. traspl. (En línea);35(1): 15-23, ene. 2015. ilus, tab
Article in Spanish | LILACS | ID: biblio-908365

ABSTRACT

Introducción: el hiperparatiroidismo secundarioes una complicación frecuente de laenfermedad renal crónica. Cinacalcet, un moduladoralostérico del receptor sensor del calcio incrementasu sensibilidad a la activación por partedel calcio iónico extracelular, demostró ser efectivoen reducir los niveles de PTH. Objetivo:Evaluar la eficacia de cinacalcet en pacientes enhemodiálisis con HPTS. Material y métodos: Se realizó un estudio retrospectivo, multicéntrico, observacional, en 76 pacientes que recibieronal menos 3 meses de cinacalcet como tratamientodel HPTS...


Introduction: secondary Hyperparathyroidism is a frequent chronic renal disease complication. Cinacalcet, an allosteric modulator of the calcium sensing receptor, increases its sensitivity to activation by extracellular calcium ions, proved to be effective in reducing PTH levels. Objetive: To evaluate cinacalcet effectiveness in hemodialysis patients with HPTS. Methods: A retrospective, multicenter, observational study was carried out, on 76 patients who received Cinacalcet for at least 3 months, as a treatment for HPTS...


Subject(s)
Male , Female , Humans , Calcium Metabolism Disorders , Drug Therapy , Hyperparathyroidism, Secondary , Hyperparathyroidism, Secondary/therapy , Renal Insufficiency, Chronic , Renal Insufficiency, Chronic/therapy , Therapeutics , Argentina , Renal Dialysis
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