ABSTRACT
Much controversy remains on the current management of Chiari I deformity (CID) in children, with many clinical, surgical and ethic-legal implications. The Brazilian Society of Pediatric Neurosurgery (SBNPed, in the Portuguese acronym) has put together a panel of experts to analyze updated published data on the medical literature about this matter and come up with several recommendations for pediatric neurosurgeons and allied health professionals when dealing with CID. Their conclusions are reported herein, along with the respective scientific background.
Subject(s)
Humans , Child , Adolescent , Arnold-Chiari Malformation/surgery , Arnold-Chiari Malformation/etiology , Arnold-Chiari Malformation/physiopathology , Arnold-Chiari Malformation/diagnostic imaging , Societies, Medical , Syringomyelia/therapy , BrazilABSTRACT
O traumatismo crânio-encefálico (TCE) é a maior causa de morbidade e mortalidade, acometendo particularmente a população jovem. Através do entendimento do conceito de lesão celular, tratamentos atuais mostram avanços medicamentosos que atuam na cascata secundária do TCE. Os autores mostram um estudo de revisão sobre os benefícios do uso da progesterona, citocolina, fator VII recombinante, endotelina, ciclosporina e amantadina no tratamento do TCE.
Traumatic brain injury (TBI) is a major cause of morbidity andmortality, particularly among young people. Understandingthe concept of cellular injury, the current management showsadvances in medical treatment in the secondary cascadeof TBI. The authors show a review study concerning to thepossible benefit of progesterone, citocholine, activatedrecombinant factor VII , endothelin, ciclosporin, amantadinein TBI treatment.