1.
Southeast Asian J Trop Med Public Health
;
1990 Dec; 21(4): 545-51
Article
in English
| IMSEAR
| ID: sea-33053
ABSTRACT
The effect on the morphology of Plasmodium yoelii of ketotifen treatment was different from that of chloroquine and other antimalarial drugs. Following administration of a low dosage of ketotifen, the parasite first developed a multilamellate pellicular complex which resembled a medullary sheath and then developed vacuoles and cavitations. The development of large multilamellate whorls consisting of a pellicular structure enclosing cytoplasm was the typical change which occurred.